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4-1BB (CD137/TNFRSF9), a member of the tumor necrosis factor receptor superfamily, is an inducible co-stimulatory receptor expressed on T cells, natural killer (NK) cells and innate immune cell populations. When present on the cell surface, 4-1BB interacts with 4-1BB ligand (4-1BBL) and induces subsequent ...
![Elabscience - Model FITC - [17A2]- E-AB-F1013C - Anti-Mouse CD3 Antibody- Brochure](/_ipx/f_webp&q_80&s_240x145/https://d32zuqhgcrpxli.cloudfront.net/eyJidWNrZXQiOiJlZS1maWxlcyIsImtleSI6ImZpbGVzLzExMzU0Ni9kb3dubG9hZC8xMDAzMDc3LzExMzU0Nl8xOV8yMDIwMTAyOTA2NDEwMzA3OTUzMTNfdGh1bWJuYWlsX2JpZy5qcGciLCJlZGl0cyI6eyJyZXNpemUiOnsiZml0IjoiY29udGFpbiIsImJhY2tncm91bmQiOnsiciI6MjU1LCJnIjoyNTUsImIiOjI1NSwiYWxwaGEiOjF9LCJ3aWR0aCI6MjQwLCJoZWlnaHQiOjE0NX19fQ== "Elabscience - Model FITC - [17A2]- E-AB-F1013C - Anti-Mouse CD3 Antibody- Brochure")
CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell ...