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Histones are a group of similar, small, highly conserved nuclear proteins that bind to DNA by their many basic residues. The histones are divided into fractions, with each fraction having a distinct amino acid composition and sequence. Histones are also classified by relatively high levels of lysine and arginine. The presence of autoantibodies to histones are frequently found in several rheumatic ...
Histones are a group of similar, small, highly conserved nuclear proteins that bind to DNA by their many basic residues. The histones are divided into fractions, with each fraction having a distinct amino acid composition and sequence. Histones are also classified by relatively high levels of lysine and arginine. The presence of autoantibodies to histones are frequently found in several rheumatic ...
Histones are a group of similar, small, highly conserved nuclear proteins that bind to DNA by their many basic residues. The histones are divided into fractions, with each fraction having a distinct amino acid composition and sequence. Histones are also classified by relatively high levels of lysine and arginine. The presence of autoantibodies to histones are frequently found in several rheumatic ...
Autoantibodies to centromeric proteins in the sera of patients with scleroderma were first described in 1980. Subsequent studies confirmed that anti-centromere antibodies (ACA) were most often found in patients with a limited form of systemic sclerosis previously referred to as CREST syndrome. These autoantibodies are also often detected in sera from patients with Raynaud’s phenomenon and ...
We, Medipan GmbH & GA Generic Assays GmbH (Germany), are leading companies in the development, manufacturing and marketing of IVD assays and instruments. Together, we have an extensive experience in immunochemistry and biomedicine, especially in tissue and cell-based IFA, ELISA and LINE & Dot assays for the diagnosis of rheumatic and other autoimmune diseases with neurologic, vascular, ...