Cell Based Assay Articles & Analysis
19 news found
Introduction We recently sat down with one of our valued customers, Dr Alexis Rossignol (Clean Cells), to discuss his experience with VIPS PRO, our cutting-edge technology designed to streamline and enhance the early stages of cell line development. This interview provides insight into Clean Cells’ quest to automate and increase single-cell seeding while having undisputable proof ...
In addition, InvivoSciences, Inc. is sponsoring a workshop during Cell Based Assays Summit in Munich Germany, December 02-04, 2013. BMG LABTECH will have a short presentation at the workshop to discuss applications of microplate readers in cell and tissue based assays. ...
Eddie Moler, PhD, Vice President of Data Science, brings over 20 years of experience in bioinformatics, predictive modeling, biomarker and diagnostics discovery, machine learning, Omics, cell-based assay technology and automation. He has held leadership and senior roles at Novartis, GE Healthcare, Quest Diagnostics, Tethys Bioscience and the US ...
To that end, we will integ rate virtual (computer) screening methods and cell-based assays to identify lead compounds that can potentially be optimized to produce a cholesterol lowering drugs. Virtual screening, which requires the availability of atomic resolution 3D structures of the target protein, provides a cost effective way to screen ...
DESCRIPTION provided by applicant Heart disease is the leading cause of death for both men and women in the US accounting for nearly of all annual deaths A high cholesterol level is well known risk factors for heart disease Although blood cholesterol can be lowered using a number of marketed drugs of which statins are the leading drugs only of patients taking these drugs are achieving the low ...
Oxford, UK – July 20, 2021 – Orbit Discovery Ltd., (“Orbit”), a privately held biopharmaceutical company focused on discovering candidate peptide therapeutics harnessing proprietary affinity and cell-based functional screening platforms, today announced that it has raised $7.6 million in funding. ...
Totalling £472,000, the grant will facilitate the implementation of droplet-based microfluidics for cell-based functional screening and significantly expand the capabilities and throughput of Orbit’s peptide display platform. ...
Phase 1b Study of SER-155 in Stem Cell Transplant Hematopoietic stem cell transplant (HSCT) is frequently used to treat lymphoma, leukemia and multiple myeloma or for people who received high doses of chemotherapy or radiation that damaged their bone marrow. While it can be curative, stem cell transplant also carries the risk of life-threatening ...
Featured in the abstract are preclinical data from in vitro and cell-based assays that demonstrate how narazaciclib’s inhibitory profile differentiates it from the FDA-approved CDK4/6 inhibitors palbociclib, ribociclib, and abemaciclib. ...
MatTek Life Sciences, a Boston-area tissue engineering company and a member of the BICO Group, announced today it has entered into a distribution agreement and strategic partnership with Cell4Pharma, a Netherlands-based company specializing in commercially available human renal cells, to distribute its products in the US as well as develop a new in vitro kidney ...
Across a variety of preclinical models, SER-155 appears to work by reducing gastrointestinal (GI) inflammation, fortifying the protective GI lining, and promoting immune cell balance in the gut. In cultured human cells designed to mimic the lining of the intestines, SER-155 protected the barrier between the colon and invading pathogens from inflammatory damage. ...
The design incorporates microbiome biomarker data from human clinical data and nonclinical human cell-based assays and in vivo disease models. The SER-155 composition aims to decrease the colonization and translocation of antibiotic-resistant bacteria in the gastrointestinal tract to decrease the incidence of bloodstream infections and ...
Orbit will also utilise other capabilities within WuXi AppTec, in particular their expertise in cell line and assay development and biophysical analysis. Incorporating these capabilities into the Orbit platform will enable functional assays to be developed against a wider range of targets, facilitating direct functional screens using novel ...
Quidel Corporation (NASDAQ: QDEL), a provider of rapid diagnostic testing solutions, cell-based virology assays and molecular diagnostic systems, announced today that it will present at the 40th Annual J.P. ...
The services range include: cell membrane preparation, signal detection and high-throughput screening. The following signal detection assays are available at Profacgen now: Cell based functional assay: second messengers (cAMP, calcium, IP1, IP3), reporter genes Ligand-receptor binding assay ...
This lead molecule (P-21) was identified through virtual screening of a million compounds and extensively validated through our in vitro as well as our functional cell-based assays. P-21 exhibited a concentration-dependent inhibition of the PCSK9/LDLR interaction with an IC50 in the nanomolar range, an increase in the level of LDLR in recombinant ...
The objective of this proposed project and the EPA Computational Toxicology program’s goals are aligned in assessing chemicals for potential risk to human health and the environment through the use of more representative multicellular human developmental neurotoxicology assays. ArunA Biomedical will develop a rapid, scalable, human pluripotent stem ...
When coupled to biochemical readouts, cell-based assays and gene expression arrays, PharmCode expedites drug discovery and provides a complete picture for target validation. ...
ByVybion
'So far the biological and protective activities of various flavonoids have been extensively studied in vitro, on cell-based assays,' explains researcher and leading author of the study, Dr Marie-Claire Toufektsian of Joseph Fourier University in Grenoble, France. ...