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Chemotherapy Articles & Analysis
201 news found
In addition, they can be applied in diverse fields, such as biological imaging, biosensing, chemotherapy drug delivery, and synergy with other therapies like magnetic hyperthermia. ...
Such APIs come in a wide range of types: chemotherapeutic, targeted, immunotherapeutic, hormone therapeutic. The APIs in chemotherapy work by interfering with the cell division mechanism to suppress cancer cell growth. ...
The study, conducted in collaboration with AstraZeneca, leverages advanced AI-driven techniques to identify subgroups of stage IV non-small cell lung cancer (NSCLC) patients who could most benefit from the addition of tremelimumab to durvalumab and chemotherapy. The research is a retrospective, multimodal analysis of the POSEIDON Phase 3 clinical trial (NCT03164616). This trial ...
"This will be especially beneficial for those who are taking THC for things like long-term pain, chemotherapy side effects, or reducing anxiety or depression." Western University researchers believe this formulation may mitigate this type of harm to chronic cannabis users. ...
Compared with conventional formulations, microspheres enable long-term and stable drug release in the body, making them a perfect choice for immunization, gene therapy and tumor chemotherapy. “With the increasing demand for targeted drug delivery and minimally invasive procedures, there is a growing need for high-quality polymer microspheres and raw materials. ...
Current treatment options for men with metastatic hormone-sensitive prostate cancer (mHSPC) include hormone therapy, such as ADT, androgen receptor pathway inhibitors plus ADT or a combination of the docetaxel chemotherapy and ADT. Despite these treatments, a large proportion of men with mHSPC will eventually experience progression to metastatic castration-resistant prostate ...
ByBayer AG
Current treatment options for men with metastatic hormone-sensitive prostate cancer (mHSPC) include hormone therapy, such as ADT, androgen receptor pathway inhibitors plus ADT or a combination of the docetaxel chemotherapy and ADT. Despite these treatments, a large proportion of men with mHSPC will eventually progress to metastatic castration-resistant prostate cancer (mCRPC), a ...
ByBayer AG
Many therapies are now available, including intraperitoneal chemotherapy, topical chemotherapy, endovascular embolization, and therapeutic radiation. ...
He was lead author on the papers describing pre-clinical synergy between multiple chemotherapeutics and trastuzumab, and the first phase II clinical trial of trastuzumab plus chemotherapy. In addition, he was the senior author of the pivotal trial of letrozole plus lapatinib – leading to an FDA approval. ...
In parallel, the ongoing Phase III clinical development programs (ARANOTE and ARASEC) with darolutamide aim to broaden its use even further by offering treatment options in the metastatic hormone-sensitive setting without concomitant chemotherapies. Darolutamide’s use in the biochemical relapse and adjuvant settings is also being investigated. ...
ByBayer AG
” A pre-clinical-stage company, PanTher Therapeutics is working to revolutionize the treatment of inoperable, locally advanced solid tumors − studying the direct delivery of existing, already proven chemotherapy agents directly onto the tumor for consistent, slow release over time. ...
ATG-037 has demonstrated promising preclinical efficacy as a monotherapy and in combination with immune checkpoint inhibitors (ICIs) and chemotherapy agents. In preclinical studies, the compound has demonstrated the ability to overcome the “hook effect” that has been observed in some anti-CD73 antibodies. ...
Food and Drug Administration (“FDA”) has approved an additional indication for PEMFEXY® (pemetrexed injection) in combination with pembrolizumab and platinum chemotherapy for the initial treatment of patients with metastatic, non-squamous, non-small cell lung cancer (“NSCLC”) with no EGFR or ALK genomic tumor aberrations. ...
The end goals are to determine whether this targeted method of delivering chemotherapy can extend survival while also improving quality of life. Although pancreatic cancer treatment has improved, pancreatic cancer patients continue to have poor outcomes – partially due to the tissue surrounding the tumor hampering intravenously delivered chemotherapy drug ...
ByxCures
Based on extensive published preclinical data (see www.lixte.com), LB-100 has the potential to significantly improve outcomes for patients undergoing various chemotherapies or immunotherapies. LIXTE’s new approach has no known competitors and is covered by a comprehensive patent portfolio. ...
The Cellworks Platform analyzes the impact of specific therapies on the patient’s personalized disease model and predicts the efficacy of specific chemotherapies. Study: ASH Abstract 2171 The purpose of the study was to examine how Differentiation Scoring derived from the Cellworks Platform, Computational Biology Model, and each Myelodysplastic Syndrome patient’s ...
“There is a clear unmet need in metastatic endometrial cancer for a therapeutic option after primary or secondary chemotherapy treatment that can meaningfully delay disease progression without debilitating side effects prior to the next round of cytotoxic therapy,” said Lehr. ...
Badhey, MD, Department of Otolaryngology, University of Massachusetts Chan Medical School, and lead author, stated, “We understand that SCC patients with positive margins after initial surgery are known to have increased risk of local recurrence, poorer rates of progression-free survival, and a need for adjuvant treatments such as radiotherapy, chemotherapy and additional ...
However, drug resistance may reveal whether it is chemotherapy drugs, targeted drugs, or immunotherapy drugs. Once drug resistance (especially multidrug resistance) is developed, cancer proliferation tends to progress faster or recurs, eventually leading to treatment failure. ...
Based on extensive published preclinical data (see www.lixte.com), LB-100 has the potential to significantly improve outcomes for patients undergoing various chemotherapies or immunotherapies. LIXTE's new approach has no known competitors and is covered by a comprehensive patent portfolio. ...