Refine by
Dna Binding Articles & Analysis
4 news found
The importance of protein DNA/RNA complexes Selectively targeting DNA or RNA has proved challenging and the effect of DNA-binding drugs on cells is analogous to a shotgun blast with multiple off-target effects which are difficult to predict. ...
Recently, Blainey demonstrated that DNA-binding proteins track the DNA helix as they slide and discovered new classes of biomolecules with sliding activity. Ongoing studies using microfluidic single-molecule assays will help understand how these molecules move; they will also identify additional classes of biomolecules that use thermal energy to ...
Scientists have known for years that age is a leading risk factor for the development of many types of cancer, but why aging increases cancer risk remains unclear. Researchers suspect that DNA methylation, or the binding of chemical tags, called methyl groups, onto DNA, may be involved. Methyl groups activate or silence genes, by affecting ...
In the body, formaldehyde can cause proteins to irreversibly bind to DNA. Laboratory animals exposed to large doses of inhaled formaldehyde over their lifetimes have developed more cancers of the nose and throat than are usual, as have workers in particle-board sawmills. ...