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Dopamine Articles & Analysis

20 news found

Protheragen-ING Releases Hundreds of APIs: Anti-Tumor APIs, Hypoglycemic APIs, Antipsychotic APIs, Bronchiectasis APIs, Antihypertensive APIs

Protheragen-ING Releases Hundreds of APIs: Anti-Tumor APIs, Hypoglycemic APIs, Antipsychotic APIs, Bronchiectasis APIs, Antihypertensive APIs

These APIs are mostly regulators of neurotransmitters such as dopamine and serotonin, which are central to mental stability. These range from conventional drugs such as chlorpromazine and haloperidol, to noveler ones such as aripiprazole. ...

ByProtheragen-ING


Cingulate Initiates Phase 3 Study of Lead Asset CTx-1301, Designed as a True Entire Active-Day Treatment for ADHD

Cingulate Initiates Phase 3 Study of Lead Asset CTx-1301, Designed as a True Entire Active-Day Treatment for ADHD

Dexmethylphenidate is part of the stimulant class of medicines and increases norepinephrine and dopamine activity in the brain to affect attention and behavior. While stimulants are the gold-standard of ADHD treatment due to their efficacy and safety, the long-standing challenge remains, providing patients entire active-day duration of action. ...

ByCingulate


Cingulate Completes Fed/Fast Study Assessing Food Effect with CTx-1301, Lead Candidate for Treatment of ADHD

Cingulate Completes Fed/Fast Study Assessing Food Effect with CTx-1301, Lead Candidate for Treatment of ADHD

Dexmethylphenidate is part of the stimulant class of medicines and increases norepinephrine and dopamine activity in the brain to affect attention and behavior. While stimulants are the gold-standard of ADHD treatment due to their efficacy and safety, the long-standing challenge remains, providing patients entire active-day duration of action. ...

ByCingulate


Cingulate Announces Agreement with Societal CDMO and Provides Clinical Update

Cingulate Announces Agreement with Societal CDMO and Provides Clinical Update

Dexmethylphenidate is part of the stimulant class of medicines and increases norepinephrine and dopamine activity in the brain to affect attention and behavior. While stimulants are the gold-standard of ADHD treatment due to their efficacy and safety, the long-standing challenge remains, providing patients entire active-day duration of action. ...

ByCingulate


XPhyto completes Rotigotine transdermal patch optimization and comparative skin absorption study

XPhyto completes Rotigotine transdermal patch optimization and comparative skin absorption study

This study is now complete and analytical results are expected to be finalized and announced within the coming days. Rotigotine is a non-ergoline dopamine agonist approved for the treatment of Parkinson’s disease and restless legs syndrome (RLS) in Europe and the United States. ...

ByXPhyto Therapeutics Corporation


Vaxxinity Completes Enrollment in Part B of UB-312 Phase 1 Clinical Trial for Parkinson’s Disease

Vaxxinity Completes Enrollment in Part B of UB-312 Phase 1 Clinical Trial for Parkinson’s Disease

PD is a chronic and progressive neurodegenerative disorder that affects predominately dopamine-producing (“dopaminergic”) neurons in the substantia nigra area of the brain. ...

ByVaxxinit


Altamira Therapeutics Completes Final Patient Enrollment in Phase 2 `TRAVERS` Clinical Trial of AM-125 for the Treatment of Acute Vertigo

Altamira Therapeutics Completes Final Patient Enrollment in Phase 2 `TRAVERS` Clinical Trial of AM-125 for the Treatment of Acute Vertigo

Betahistine is known to increase the release of histamine, acetylcholine, dopamine and norepinephrine in the brain. It increases cochlear, vestibular and cerebral blood flow and facilitates vestibular compensation and inhibits neuronal firing in the vestibular nuclei. ...

ByAuris Medical AG


BlueRock Therapeutics Announces First Patient Dosed in Canada in Phase 1 Trial in Patients with Advanced Parkinson’s Disease

BlueRock Therapeutics Announces First Patient Dosed in Canada in Phase 1 Trial in Patients with Advanced Parkinson’s Disease

About Parkinson’s Disease Parkinson’s disease is a progressive neurodegenerative disorder caused by nerve cell damage in the brain, leading to decreased dopamine levels. The worsening of motor and non-motor symptoms is caused by the loss of dopamine-producing neurons. ...

ByBlueRock Therapeutics


BlueRock Therapeutics Announces Closeout of First Cohort in Phase 1 Trial in Patients with Advanced Parkinson’s Disease

BlueRock Therapeutics Announces Closeout of First Cohort in Phase 1 Trial in Patients with Advanced Parkinson’s Disease

About Parkinson’s Disease Parkinson’s disease is a progressive neurodegenerative disorder caused by nerve cell damage in the brain, leading to decreased dopamine levels. The worsening of motor and non-motor symptoms is caused by the loss of dopamine-producing neurons. ...

ByBlueRock Therapeutics


BlueRock Therapeutics Receives FDA Fast Track Designation for DA01 in the Treatment of Advanced Parkinson`s Disease

BlueRock Therapeutics Receives FDA Fast Track Designation for DA01 in the Treatment of Advanced Parkinson`s Disease

About Parkinson’s Disease Parkinson’s disease is a progressive neurodegenerative disorder caused by nerve cell damage in the brain, leading to decreased dopamine levels. The worsening of motor and non-motor symptoms is caused by the loss of dopamine-producing neurons. ...

ByBlueRock Therapeutics


BlueRock Therapeutics Announces First Patient Dosed with DA01 in Phase 1 Study in Patients with Advanced Parkinson`s Disease

BlueRock Therapeutics Announces First Patient Dosed with DA01 in Phase 1 Study in Patients with Advanced Parkinson`s Disease

In this study, subjects undergo surgical transplantation of the dopamine-producing cells into the putamen. The first surgery was performed by Dr. ...

ByBlueRock Therapeutics


BlueRock Therapeutics Receives Permission from Health Canada for DA01 Trial in Parkinson’s Disease

BlueRock Therapeutics Receives Permission from Health Canada for DA01 Trial in Parkinson’s Disease

About Parkinson’s Disease Parkinson’s disease is a progressive neurodegenerative disorder caused by nerve cell damage in the brain, leading to decreased dopamine levels. The worsening of motor and non-motor symptoms is caused by the loss of dopamine-producing neurons. ...

ByBlueRock Therapeutics


BlueRock Therapeutics in Collaboration with Memorial Sloan Kettering Cancer Center Receives IND Clearance for DA01 in Parkinson`s Disease

BlueRock Therapeutics in Collaboration with Memorial Sloan Kettering Cancer Center Receives IND Clearance for DA01 in Parkinson`s Disease

“This is a big step for the stem cell field – to finally test a truly “off-the-shelf” dopamine neuron product in human PD patients,” said Lorenz Studer, MD, scientific co-founder of BlueRock and Director, Center for Stem Cell Biology at MSK. ...

ByBlueRock Therapeutics


S1 Biopharma Announces Expanded Analysis Of Phase 2A Data On Lorexys™ For Treatment Of Hypoactive Sexual Desire Disorder Based On Pgic Scale To Be Presented At 2019 Isswsh/Issm Joint Meeting

S1 Biopharma Announces Expanded Analysis Of Phase 2A Data On Lorexys™ For Treatment Of Hypoactive Sexual Desire Disorder Based On Pgic Scale To Be Presented At 2019 Isswsh/Issm Joint Meeting

The therapy is designed to restore the balance of key neurotransmitters in the brain – dopamine, serotonin and norepinephrine – that are known to regulate sexual inhibition and sexual excitation. ...

ByS1 Biopharma, Inc.


EndoLogic Announces FDA Accepts Cardiac Safety Trial for Renzapride in Patients with Gastroparesis

EndoLogic Announces FDA Accepts Cardiac Safety Trial for Renzapride in Patients with Gastroparesis

Currently, treatment options are limited with only one drug, metoclopramide (brand name Reglan®), a four times daily oral dopamine D2 receptor antagonist, approved for the treatment of gastroparesis; however, treatment with metoclopramide for more than 12 weeks should be avoided due to the risk of tardive dyskinesia. ...

ByEndoLogic LLC


Clinical study authorised in Sweden for the investigation of CDNF and Renishaw drug delivery system in Parkinson`s patients

Clinical study authorised in Sweden for the investigation of CDNF and Renishaw drug delivery system in Parkinson`s patients

The Medicines Agency of Sweden, MPA, has authorised Herantis Pharma Plc and Renishaw plc's randomised, placebo-controlled Phase 1-2 clinical study, for the investigation of Cerebral Dopamine Neurotrophic Factor (CDNF) and Renishaw's chronic drug delivery system, in Parkinson's patients. ...

ByRenishaw plc


EndoLogic Acquires Renzapride from Alizyme, plc

EndoLogic Acquires Renzapride from Alizyme, plc

Currently, only one drug, metoclopramide (brand name Reglan®) a dopamine D2 receptor antagonist, is approved for the treatment of gastroparesis. ...

ByEndoLogic LLC


S1 Biopharma And Ckd Pharmaceuticals Announce Commercialization Agreement For Lorexys™ In South Korea For Treatment Of Hypoactive Sexual Desire Disorder (Hsdd) In Women

S1 Biopharma And Ckd Pharmaceuticals Announce Commercialization Agreement For Lorexys™ In South Korea For Treatment Of Hypoactive Sexual Desire Disorder (Hsdd) In Women

It has a unique mechanism of action designed to restore the balance of three neurotransmitters – dopamine, serotonin and norepinephrine – that are known to regulate sexual inhibition and sexual excitation. ...

ByS1 Biopharma, Inc.


Lauren Sciences LLC awarded second Michael J. Fox Foundation grant to further develop V-Smart Therapeutic for Parkinson`s disease

Lauren Sciences LLC awarded second Michael J. Fox Foundation grant to further develop V-Smart Therapeutic for Parkinson`s disease

GDNF might be able to restore function of degenerating dopamine-producing-cells and thus retard progression of the disease and even reverse the course of the disease. ...

ByLauren Sciences LLC


Women who start prenatal vitamins early are less likely to have children with autism

The COMT enzyme, well known for its role in dopamine degradation, is activated during early neurodevelopment. Structural and functional brain differences have been described across COMT genotypes, particularly in the hippocampal and prefrontal cortex, regions affected by autism. ...

ByNational Institute of Environmental Health Sciences (NIEHS)

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