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Drug Target Articles & Analysis
196 news found
Combined with nanotechnology, "smart" drugs can actively target tumors by binding to corresponding receptors on tumor cells through interactions with phenotype-specific ligands conjugated to the delivery vehicle. ...
As an expert in providing solutions to assist virology and microbiology research, Creative Diagnostics has announced the expansion and enhancement of its comprehensive Drug Discovery Services to help scientists advance antiviral therapeutic development, including target selection and validation, hit selection and optimization, and preclinical development. ...
Transdermal Delivery: Overcoming Natural Barriers Traditional transdermal drug delivery has struggled with the skin’s natural barrier, the stratum corneum, which limits effective drug absorption. ...
They are also critical components in antibody-drug conjugate (ADC) linkers, facilitating targeted drug delivery, and in PROTAC linkers, enabling the development of novel protein degradation therapies. ...
This iterative process facilitates the creation of drug candidates that not only show promise in early trials but are also more likely to advance through the rigorous drug development pipeline. ...
Kelly Bugatti, BOC Sciences is set to host an informative webinar that will delve into the latest advancements in utilizing Peptide-Drug Conjugates (PDCs) for the targeted treatment of Pulmonary Fibrosi BOC Sciences has been organizing regular webinars in the fields of life sciences, drug discovery, and chemistry. ...
Among the 15 approved ADCs globally, notable therapies like Trodelvy and Zynlonta utilize PEG linkers to enhance drug stability and targeting. The benefits of incorporating PEGs into ADC formulations are significant, including improved solubility, prolonged circulation time, and reduced immunogenicity, all of which contribute to more effective cancer treatments. ...
Idiopathic pulmonary fibrosis (IPF) is a devastating disease characterized by progressive scarring of the lungs, which severely impairs lung function over time. Developing effective treatments for IPF has been a challenge for the medical community, as the mechanisms driving this disease are complex and not fully understood. To accelerate drug discovery, animal models that closely mimic the ...
CD Formulation, a leader in biotechnological innovation, is advancing the field of targeted drug delivery with its customized metal-organic frameworks (MOFs) services. ...
Research institutions focusing on pharmaceutical formulation, cosmetic development, and healthcare solutions will find value in their specialized services, which include: l Advanced Drug Delivery System Development: Targeted drug delivery, injectable formulations, and more. l Pharmaceutical Analytical Methods and Testing Services: Comprehensive ...
The process of antipsychiatric drug development typically involves several stages, including identifying potential drug targets, conducting preclinical research to test the safety and efficacy of potential drug candidates, and then moving on to clinical trials to further evaluate the drug’s effectiveness ...
These hydrogels are pivotal in medical devices, regenerative medicine, drug delivery systems, 3D cell culture, and wound healing." Diverse Product Offering: Biopharma PEG’s multi-arm PEG products are available with various branching structures and functional groups to meet the specific needs of researchers and developers in the medical and bioorganic fields. ...
For example, the 113-O12B-Lipid Nanoparticles Targeted to Lymph Nodes (Catalog: CDCLP24-013-L), the specific lipids synthesized, can allow specific lymph node targeting. ...
CD ComputaBio, a pioneering provider of computational biology services, has recently introduced its advanced Computer-Aided Drug Design (CADD) services, revolutionizing the drug discovery landscape. ...
By optimizing the release profile of drugs, this platform can improve patient compliance and reduce the risk of side effects associated with fluctuating drug levels in the body. ...
These microneedles are composed of a biocompatible material that dissolves upon insertion, allowing for controlled and targeted drug release. The dissolving microneedle preparation services offered by CD Formulation provide a comprehensive solution for pharmaceutical companies looking to optimize drug delivery. ...
CD BioSciences, a US-based CRO serving the global life science research community, has announced the launch of its new services to study the Mechanistic Target of Rapamycin (mTOR) in diabetes and metabolism research. The mechanistic Target of Rapamycin is a serine/threonine protein kinase that is inhibited by rapamycin, a bacterial compound originally isolated ...
CD Formulation's transdermal patch drug delivery system services are designed to optimize formulations, ensuring the efficient and precise delivery of drugs across the skin barrier. ...
Microspheres, tiny spherical particles typically ranging from 1 to 100 microns in diameter, offer immense potential for targeted drug delivery. By encapsulating active pharmaceutical ingredients (APIs) within these microspheres, drugs can be delivered directly to specific tissues or organs, resulting in improved therapeutic efficacy and reduced ...
By leveraging cutting-edge conjugation methods, targeting drug delivery solutions, and RNAi delivery systems, scientists can gain unprecedented control over the design and synthesis of bioconjugates. ...