Immune Regulation Articles & Analysis
13 news found
CD Genomics, a renowned leader in genomics and next-generation sequencing (NGS) applications, has unveiled its cutting-edge HLA typing solutions, revolutionizing immune profiling and transplantation compatibility assessment. The human leukocyte antigen (HLA) system plays a crucial role in immune regulation and determining transplantation ...
Cytokines and growth factors are chemical messengers that mediate intracellular communication to regulate cellular and nuclear functions. These soluble messengers bind cell surface receptors, which in turn initiate a transmembrane and intracellular cascade of events in the signal transduction process. ...
Title: Dual targeting of innate and adaptive immune checkpoints with a PD-L1/SIRPα bispecific macrophage engager to promote anti-tumor activity Abstract No.: 1211 The anti-PDL1/SIRPα bispecific antibody ES019, designed for tumor cell and immune cell dual targeting, is capable of reactivating macrophages and T cells to kill cancer cells with the ...
Presentation Details Title: PMC-309, a highly selective anti-VISTA antibody reverses immunosuppressive TME to immune-supportive TME Abstract Number: 751 Presentation Type: Poster Presentation Onsite Location: Poster Hall Date: November 10, 2022 9 a.m. ...
Focusing on key disease areas such as tumor and immune regulation, metabolism and digestive system, and central nervous system, Fosun Pharma has built and formed technology platforms for small molecule innovative drugs, antibody drugs, and cell therapy, and actively explores RNA, gene therapy, ADC, Targeting cutting-edge technology fields such as protein ...
Cytokines play an important role in physiological and pathological processes such as immune cell differentiation and subset development, immune regulation, inflammatory response, and tumor metastasis. ...
TNF’s primary role involves the regulation of immune cells, but it is also a pyrogen that induces fever and inflammation. ...
AstroRx® also has the potential in MS to support the damaged cells by releasing neurotrophic substances that protect nerve cells, lowering the amount of free radicals, regulating the immune system and eliminating toxic substances released in the pathological state. ...
Elias says, “We believe we have discovered a master pathway that regulates immune checkpoint inhibitors in the lung, and in turn controls the ability of tumor cells to spread to the lung and grow once they’re in the lung.” He notes that, “these are very novel observations that give us a completely new vision for the processes that ...
Low dose arm of the study met the co-primary endpoints of percent change in Eczema Area and Severity Index (EASI) score from baseline, and incidence of treatment-emergent adverse events, through week 16 First trial to assess the effects of blocking OX40-Ligand, a key immune system regulator, in patients with moderate-to-severe atopic dermatitis Data support ...
Probiotics can inhibit Helicobacter pylori through immune or non-immune mechanisms. First of all, by taking probiotics, this first line of defense may be stronger because it produces antibacterial substances that compete with Helicobacter pylori to adhere to receptors, stimulate the production of mucin, and stabilize the intestinal mucosal barrier. ...
Bilirubin, a component extracted from pig blood, is a substance that has a strong antioxidant effect that removes active oxygen, and is known to have immune system regulating and anti-inflammatory effects. Reactive oxygen species play a role in removing bacteria and viruses in the body, but if there are too many of them, they attack normal cells and cause ...
The team applied the ecosystem services model, an approach used by environmental ecologists to identify and assess the benefits humans receive from natural environmental ecosystems – supporting services for structure, provisioning services to feed the system, and regulating services to maintain system balance. Applied to the infant gut microbiome, the microorganisms that ...