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Inflammatory Condition Articles & Analysis

28 news found

Protheragen-ING Offers a Full Range of Nonsteroidal Anti-inflammatory APIs, Including Celecoxib and Crisaborole

Protheragen-ING Offers a Full Range of Nonsteroidal Anti-inflammatory APIs, Including Celecoxib and Crisaborole

To address this need, Protheragen-ING continues to prove itself as a top supplier of nonsteroidal anti-inflammatory APIs (NSAIDs), a class of anti-inflammatory APIs. These widely used compounds are helpful to manage various inflammatory conditions such as arthritis, musculoskeletal injuries, toothaches, menstrual pain and ...

ByProtheragen-ING


Dual Benefits of Compound 17B For Pulmonary Arterial Hypertension

Dual Benefits of Compound 17B For Pulmonary Arterial Hypertension

Pulmonary arterial hypertension (PAH) is a progressive, life-threatening condition characterized by increased pulmonary arterial pressure, vascular remodeling, and persistent inflammation. ...

BySCIREQ - an emka TECHNOLOGIES Company


Treating Acute Inflammatory Lung Disease: The Promise of Trimannose-Coupled Antimir-21

Treating Acute Inflammatory Lung Disease: The Promise of Trimannose-Coupled Antimir-21

Recent advances in the fight against severe acute inflammatory lung diseases, including COVID-19, have revealed a promising new approach to treating pulmonary hyperinflammation and long-term lung damage such as fibrosis. A groundbreaking study has developed a first-in-class, carbohydrate-coupled inhibitor of microRNA-21 (RCS-21), which shows significant potential as a therapeutic agent. This ...

BySCIREQ - an emka TECHNOLOGIES Company


Gesynta Pharma prepares Phase II study of GS-248 in endometriosis following ground-breaking data from a preclinical proof-of-concept study

Gesynta Pharma prepares Phase II study of GS-248 in endometriosis following ground-breaking data from a preclinical proof-of-concept study

Gesynta Pharma AB today announces the decision to advance the development of its clinical-stage drug candidate GS-248 in endometriosis - a chronic inflammatory condition affecting approximately 10 percent of all women of reproductive age. ...

ByGesynta Pharma AB


AOBiome Therapeutics Announces Appointment of Dr. Judith Ng Cashin as Chief Medical Officer

AOBiome Therapeutics Announces Appointment of Dr. Judith Ng Cashin as Chief Medical Officer

("AOBiome"), a leading clinical-stage microbiome company focusing on the research and development of a novel class of drugs for inflammatory conditions, central nervous system disorders, and other systemic diseases, today announced that Dr. ...

ByAOBiome Therapeutic, LLC


Tetra Bio-Pharma Announces Licensing Agreement with True North for Patented CBD Technology

Tetra Bio-Pharma Announces Licensing Agreement with True North for Patented CBD Technology

They bring a combined experience of over 100 years in research and clinical care of people dealing with chronic pain and inflammatory conditions. Panag's development pipeline of pain relief products include topical, oral, and ocular delivery solutions for challenging molecules. ...

ByTetra Bio-Pharma


Sangamo Therapeutics Announces Dosing of First Patient in Phase 1/2 Clinical Study of Investigational CAR-Treg Cell Therapy TX200 in Kidney Transplantation

Sangamo Therapeutics Announces Dosing of First Patient in Phase 1/2 Clinical Study of Investigational CAR-Treg Cell Therapy TX200 in Kidney Transplantation

“We believe that CAR-Tregs are the next frontier of cell therapy and represent a potentially transformational approach to solid organ transplantation as well as to many challenging autoimmune and inflammatory conditions. The STEADFAST Phase 1/2 study is an important milestone for genomic medicine that we anticipate will yield insights regarding CAR-Treg ...

BySangamo Therapeutics


Preventing Wound Infections and Complications at Urgent Care

Preventing Wound Infections and Complications at Urgent Care

Patients at Higher Risk of Wound Infections Some urgent care patients may have underlying conditions that could increase their risk of wound infections either due to the condition itself or the drugs used to treat it. ...

ByKitoTech Medical, Inc.


AOBiome’s B244 demonstrated positive results from its Phase 2b trial for both Pruritus (Itch) and Appearance of Atopic Dermatitis (Eczema)

AOBiome’s B244 demonstrated positive results from its Phase 2b trial for both Pruritus (Itch) and Appearance of Atopic Dermatitis (Eczema)

AOBiome Therapeutics, a clinical stage biotechnology company focused on transforming human health by developing topical biologic therapies for systemic inflammatory conditions, announced positive pivotal Phase 2b results from its trial evaluating B244 in both pruritus (itch) and appearance of atopic dermatitis (eczema). ...

ByAOBiome Therapeutic, LLC


Suono Bio, Inc. Announces Formulation-Agnostic Platform for the Delivery of RNA Therapeutics

Suono Bio, Inc. Announces Formulation-Agnostic Platform for the Delivery of RNA Therapeutics

In addition to previously demonstrating the preclinical use of siRNAs for treating inflammatory conditions, this latest publication demonstrates the ability to knockdown endogenous genes, including Ctnnb1, the gene encoding for beta-catenin, which plays a role in tumorigenesis in colorectal cancers, for example. ...

BySuono Bio


Neurent Medical Receives FDA Clearance for NEUROMARK, a Novel Multi-Point Nerve Disruption Treatment for Chronic Rhinitis

Neurent Medical Receives FDA Clearance for NEUROMARK, a Novel Multi-Point Nerve Disruption Treatment for Chronic Rhinitis

GALWAY, Ireland–Neurent Medical, a company pioneering innovative treatments for chronic inflammatory sino-nasal diseases, today announced Food and Drug Administration (FDA) clearance of its proprietary NEUROMARK™ Rhinitis Neurolysis Therapy™ (RNT). ...

ByNeurent Medical


AOBiome Achieves Landmark Recruitment Goal in Largest Clinical Trial Ever Powered by a Live Topical Biotherapeutic

AOBiome Achieves Landmark Recruitment Goal in Largest Clinical Trial Ever Powered by a Live Topical Biotherapeutic

Additionally, recently published immunology data demonstrates that B244 can reduce the inflammatory and pruritic cytokines IL-4, IL-5, IL-13, and IL-31. About AOBiome Therapeutics, Inc. AOBiome Therapeutics, Inc. is a Cambridge, MA-based life sciences company focused on transforming human health by developing topical biologic therapies for local, nasal and systemic ...

ByAOBiome Therapeutic, LLC


AB2 Bio expands Phase 3 trial of Tadekinig alfa in monogenic HLH

AB2 Bio expands Phase 3 trial of Tadekinig alfa in monogenic HLH

There are currently no drugs specifically approved to treat IL-18 driven monogenic HLH and severe inflammatory conditions; disability and death are common outcomes. Dr. Michael Soldan, CEO of AB2 Bio commented: “We are pleased to expand this Phase 3 trial of Tadekinig alfa to adults and thus offering participation in this trial to a wider patient ...

ByAB2 Bio Ltd.


AOBiome`s 30 Patient Study Using New Shelf-Stable Formulation of its Ammonia Oxidizing Bacteria (AOB) Shows Significant Reduction of Itch Levels in Both Pediatric and Adult Subjects who Suffer from Eczema

AOBiome`s 30 Patient Study Using New Shelf-Stable Formulation of its Ammonia Oxidizing Bacteria (AOB) Shows Significant Reduction of Itch Levels in Both Pediatric and Adult Subjects who Suffer from Eczema

(“AOBiome”), a leading clinical-stage microbiome company focusing on inflammatory conditions, has announced the completion of a cosmetic study investigating the safety and effects of its novel AOB formulation on subjects with mild to moderate eczema. ...

ByAOBiome Therapeutic, LLC


Imspex’s patent portfolio grows

Imspex’s patent portfolio grows

This is the platform that is used to screen for disease indications such as bacterial and viral respiratory tract infections, Group B Streptococcus infection, lung cancer and other chronic inflammatory respiratory conditions. We are pleased to be able to extend use of this technology from its roots in industrial and environmental applications to making a ...

ByImspex Diagnostics Ltd.


BenevolentAI announces first patient dosed in its Atopic Dermatitis clinical trial

BenevolentAI announces first patient dosed in its Atopic Dermatitis clinical trial

Atopic Dermatitis is characterised as a chronic relapsing inflammatory skin condition which manifests as itchy, inflamed skin. The addressable global patient population is estimated at 230 million. ...

ByBenevolent


Gesynta Pharma initiates Phase II study of its first-in-class drug candidate GS-248 in patients with systemic sclerosis

Gesynta Pharma initiates Phase II study of its first-in-class drug candidate GS-248 in patients with systemic sclerosis

Study results are expected towards the end of 2021 and will provide the basis for future clinical trials both in systemic sclerosis and potentially other chronic inflammatory diseases. Systemic sclerosis is a progressive, autoimmune disease that leads to serious damage to the microvasculature. ...

ByGesynta Pharma AB


TIKOMED’S ILB® resolves inflammatory scarring and promotes functional tissue repair in data published in npj Regenerative Medicine

TIKOMED’S ILB® resolves inflammatory scarring and promotes functional tissue repair in data published in npj Regenerative Medicine

As such, it represents a potential step-change in the treatment of many conditions where inflammatory scarring compromises tissue function”. ...

ByTIKOMED AB


AB2 Bio and WuXi Biologics Announce Collaboration to Accelerate Commercial-Scale Manufacturing of Tadekinig alfa

AB2 Bio and WuXi Biologics Announce Collaboration to Accelerate Commercial-Scale Manufacturing of Tadekinig alfa

There are currently no drugs specifically approved to treat IL-18 driven monogenic HLH and severe inflammatory conditions, disability and death are common outcomes. Michael Soldan, CEO of AB2 Bio commented: “We are eager to progress Tadekinig alfa to the market, and our manufacturing agreement with WuXi Biologics will accelerate commercial scale ...

ByAB2 Bio Ltd.


AOBiome Reports Successful Clinical Trials (Phase 2a in Adults and Phase 1b in Pediatrics) in Pruritus (Itch) Associated with Atopic Dermatitis: Initiates Phase 2b Clinical Trial in Adults

AOBiome Reports Successful Clinical Trials (Phase 2a in Adults and Phase 1b in Pediatrics) in Pruritus (Itch) Associated with Atopic Dermatitis: Initiates Phase 2b Clinical Trial in Adults

Pre-clinical results have shown that the bacteria exert an anti-inflammatory effect on certain markers associated with itch. Company studies have also shown the potential antimicrobial mechanism of action that contribute to the reduction of pathogenic bacteria infecting the established skin lesions," said Board of Director, Dr. ...

ByAOBiome Therapeutic, LLC

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