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Lung Volume Articles & Analysis
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Idiopathic pulmonary fibrosis (IPF) is a devastating disease characterized by progressive scarring of the lungs, which severely impairs lung function over time. Developing effective treatments for IPF has been a challenge for the medical community, as the mechanisms driving this disease are complex and not fully understood. To accelerate drug discovery, animal models that closely mimic the ...
Tuberculosis (TB) and Human Immunodeficiency Virus (HIV) are major global health threats. Their interaction worsens disease severity, as HIV reduces CD4+ T cells, making individuals more vulnerable to TB. Despite progress, an effective animal model that mimics human immune response during HIV/TB co-infection has been lacking, hindering treatment and vaccine development. Bohorguez et al. ...
In the realm of pulmonary research, the search to understand complex lung conditions has led to the development of various animal models. Among these, a new murine model from Tsijis et al stands out for its potential to investigate flow-induced pulmonary hypertension (PH) and compensatory lung growth (CLG). This blog outlines this innovative model, its significance, and the method of ...
Until now, the only other options for these patients were invasive treatments such as lung volume reduction surgery or lung transplantation. The one-way Zephyr Valves are placed in a selected lobe of the lung (generally the most diseased lobe and with little to no collateral ventilation) during a bronchoscopic procedure to ...
ReDS™ Pro is used to measure the absolute lung fluid volume in patients, which has strong correlation with symptoms of Coronary Heart Failure (CHF). It is a non-invasive method that takes only 45 seconds to measure. Lung fluid assessment with ReDS™ Pro is proven to be as accurate as that measured by a CT scan. ...
About Idiopathic Pulmonary Fibrosis Fibrosis is characterized by an excessive deposition of extracellular matrix components interfering with normal organ function. In the lung, fibrosis interferes with normal gas exchange and reduces lung volumes, leading to shortness of breath. ...
The AeriSeal System is used to close collateral air channels in a target lung lobe of a patient with severe COPD/emphysema, making the patient eligible to then undergo Bronchoscopic Lung Volume Reduction (BLVR) with Zephyr Valves. ...
It is not inconceivable that we will stop conducting lung function tests and perform a CT scan instead to determine lung capacity, residual volume, flow characteristics, and emphysema score. ...
ByFluidda
Significant differences between the treatment and control lungs were observed for airway volume (27% and 17% at TLC and FRC, respectively) as well as for the change in airway volume between FRC and TLC (48% in treatment lung and 5% in control lung). This suggests that in addition to a static improvement in airway ...
ByFluidda