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Preclinical Drug Development Articles & Analysis

16 news found

Validating The BLEO-Induced Mouse Model For Drug Discovery

Validating The BLEO-Induced Mouse Model For Drug Discovery

Idiopathic pulmonary fibrosis (IPF) is a devastating disease characterized by progressive scarring of the lungs, which severely impairs lung function over time. Developing effective treatments for IPF has been a challenge for the medical community, as the mechanisms driving this disease are complex and not fully understood. To accelerate drug discovery, animal models that closely mimic the ...

BySCIREQ - an emka TECHNOLOGIES Company


Ace Therapeutics Unveils Model Development Services to Power Up Psychiatric Drug R&D

Ace Therapeutics Unveils Model Development Services to Power Up Psychiatric Drug R&D

Ace Therapeutics, a preclinical contract research organization (CRO) actively engaged in mental illness research, has announced the launch of its model development services, which aim to revolutionize psychiatric drug research and development. ...

ByAce Therapeutics


Alfa Chemistry Leads the Way in Tailored Preclinical Drug Research Solutions

Alfa Chemistry Leads the Way in Tailored Preclinical Drug Research Solutions

Our team recognizes this need and has developed a suite of services to support drug development at its earliest stages. ...

ByAlfa Chemistry


Six Signs your Clinical Development Leadership is Failing

Six Signs your Clinical Development Leadership is Failing

Lack of funding, safety issues, and patient dropouts are some of the struggles clinical development teams face. Some problems you as a leader may face may not always be in your control, e.g., lack of funding. ...

ByBrio Group


VeriSIM Life Secures a Federal Grant to Create a Drug Combinatorial Platform Against COVID-19

VeriSIM Life Secures a Federal Grant to Create a Drug Combinatorial Platform Against COVID-19

VeriSIM Life has developed a whole-body biosimulation platform driven by AI and machine learning (ML), that accurately predicts the clinical efficacy of new drugs before human trials. ...

ByVeriSIM Life


Cell Apoptosis Kits at Creative Biogene: Efficient and Convenient

Cell Apoptosis Kits at Creative Biogene: Efficient and Convenient

Our scientists will help fellows proceed with mitochondria-focused design, validation, and test experiment in support of preclinical stages of pharmaceutical drug development," the marketing manager at Creative Biogene said. ...

ByCreative Biogene-Mitochondrial Research


GeneCentric Publishes New Data Comparing Predictive Immune Response Profiles in Patients Treated with Checkpoint Inhibition or IL-2

GeneCentric Publishes New Data Comparing Predictive Immune Response Profiles in Patients Treated with Checkpoint Inhibition or IL-2

With this work we were able to develop a novel IL-2 response signature that may have prognostic ...

ByGeneCentric Therapeutics, Inc.


GeneCentric to Present Initial Clinicogenomic Results from the GARNER High-Risk Non-Muscle Invasive Bladder Cancer Real-World Study

GeneCentric to Present Initial Clinicogenomic Results from the GARNER High-Risk Non-Muscle Invasive Bladder Cancer Real-World Study

The study is a collaboration between the Department of Urology at Erasmus MC Cancer Institute (EMC), Janssen Research & Development, LLC (Janssen) and GeneCentric Therapeutics. The collaboration, led at EMC by Tahlita Zuiverloon, MD, PhD, Principal Investigator at the Erasmus MC Urothelial Cancer Research Group (EUCRG), involves retrospective longitudinal, genomic analysis of ...

ByGeneCentric Therapeutics, Inc.


Fc Fusion Protein Production Service Now Available at Profacgen

Fc Fusion Protein Production Service Now Available at Profacgen

Profacgen, a state-of-the-art protein service provider located in the USA, provides comprehensive one-stop services for pre-clinical drug development, aiming to evaluate and improve the efficacy and safety of new drug candidates. ...

ByProfacgen


GeneCentric to Present Discovery and Initial Clinical Utility of a Novel RNA-Based Gene Signature That Predicts Treatment Response in Patients with Head and Neck Cancer

GeneCentric to Present Discovery and Initial Clinical Utility of a Novel RNA-Based Gene Signature That Predicts Treatment Response in Patients with Head and Neck Cancer

Louis and Neil Hayes, MD, MPH, at the University of Tennessee Health Science Center’s Center for Cancer Research to discover and develop new prognostic and/or predictive signatures and related tests to aid in the selection of treatments for HNSCC. ...

ByGeneCentric Therapeutics, Inc.


GeneCentric Therapeutics Identifies RNA-Based Genomic Markers of Clinical Response in Lung Cancer

GeneCentric Therapeutics Identifies RNA-Based Genomic Markers of Clinical Response in Lung Cancer

“While our work has expanded well beyond the lung, the actionable clinical and genomic datasets we have developed have led to multiple signatures and related prototype tests. ...

ByGeneCentric Therapeutics, Inc.


GeneCentric Therapeutics Closes $7.5 Million Series B1 Financing

GeneCentric Therapeutics Closes $7.5 Million Series B1 Financing

By applying its rT(I)ME Explorer technology, GeneCentric is expanding drug response biomarkers and identifying new targets to enable more effective and efficient drug development. ...

ByGeneCentric Therapeutics, Inc.


Thermo Fisher Scientific Showcases Investment and Innovation During CPhI Worldwide 2021

Thermo Fisher Scientific Showcases Investment and Innovation During CPhI Worldwide 2021

Louis, Mo. with 58,000 square feet of manufacturing and production support at the 5KL processing scale and continued support at the 2KL processing scale. To accelerate preclinical development for biologic drug developers, Thermo Fisher recently introduced its enhanced Quick to Clinic solution, designed to help biopharma ...

ByThermo Fisher Scientific


GeneCentric Therapeutics Collaborates with Labcorp to Develop Novel RNA-Based Oncology Diagnostics

GeneCentric Therapeutics Collaborates with Labcorp to Develop Novel RNA-Based Oncology Diagnostics

RNA-based gene signatures will be co-developed alongside Labcorp Drug Development, while subsequent tests will be deployed to major academic and community cancer centers through Labcorp Diagnostics. ...

ByGeneCentric Therapeutics, Inc.


Thermo Fisher Scientific To Showcase Investments and Innovation at DCAT Week 2021

Thermo Fisher Scientific To Showcase Investments and Innovation at DCAT Week 2021

This week, Thermo Fisher Scientific will highlight its investments and innovations over the past 12 months across its global pharma services network, which have been focused on areas of accelerated demand including cell and gene therapy, drug product development, biologics manufacturing and clinical supply chain services. ...

ByThermo Fisher Scientific, LIMS & Laboratory Software


Atomwise Partners with Global Research Teams to Pursue Broad-Spectrum Treatments Against COVID-19 and Future Coronavirus Outbreaks

Atomwise Partners with Global Research Teams to Pursue Broad-Spectrum Treatments Against COVID-19 and Future Coronavirus Outbreaks

Each collaborative project will develop drug candidates with demonstrable broad-spectrum capability, providing potential long-term benefit for future coronavirus outbreaks. ...

ByAtomwise Inc.

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