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Mammatyper Medical Equipment & Supplies
4 equipment items found
Manufactured by:Cerca Biotech based inBerlin, GERMANY
The progesterone receptor (PGR) also belongs to the gene family of steroid receptors. Upon binding of progesterone, the receptor is activated and modifies expression of several downstream genes. Estrogen and progesterone receptors are found in Breast Cancer cells that depend on estrogen and related hormones (such as progesterone) to grow. All patients with invasive Breast Cancer or a Breast ...
Manufactured by:Cerca Biotech based inBerlin, GERMANY
The Estrogen receptor 1 gene (ESR1) belongs to the family of steroid receptors. The protein is expressed intracellularly. It is a transcription factor regulating the expression of genes and is activated by estrogen. Estrogen receptors are overexpressed in about 70 % of all Breast Cancer cases. There are hypotheses, that overexpression causes tumourigenesis. ESR1 overexpressing tumours can be ...
Manufactured by:Cerca Biotech based inBerlin, GERMANY
ERBB2 is the name of the gene for human epidermal growth factor receptor 2 (HER2). This receptor is a cell surface protein which belongs to the family of epidermal growth factor receptors. ERBB2 activation stimulates cell proliferation and inhibits programmed cell death. ERBB2 has an important role in Breast Cancer. About 20 % of all Breast Cancers show an overexpression of this receptor, which ...
Manufactured by:Cerca Biotech based inBerlin, GERMANY
The marker of proliferation MKI67 is a nuclear protein associated with cell proliferation. MKI67 protein is present during all active phases of the cell cycle (G1, S, G2, and mitosis), but is absent from resting cells (G0). In Breast Cancer MKI67 expression is a prognostic marker for survival and tumour ...