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Stanford Chemicals - Model 040-000-284 - Hydroxychloroquine Sulfate, CAS 747-36-4
Hydroxychloroquine is usually taken with food or milk to prevent stomach upset. It was approved for medical use in the United States in 1955. It regulates the activity of the immune system and modifies the underlying disease process, rather than simply treating the symptoms.
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active pharmaceutical ingredient
COVID 19
stomach upset
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disease process
multiple myeloma
immune system
myeloma cell
rheumatoid arthritis
- Synonyms: 2-[[4-[(7-Chloro-4-quinolinyl)amino]pentyl]ethylamino]ethanol sulfate
- Key words: Autophagy inhibitor; also TLR9 inhibitor; COVID-19
- Related products: Remdesivir (development code GS-5734); Losartan Potassium, cell metabolism, autophagy
- Product Name: Hydroxychloroquine Sulfate
- CAS Registry Number: 747-36-4
- Molecular Formula: C18H28ClN3O5S
- Molecular Weight: 433.95 g/mol
- Purity: ≥99% (HPLC)
- Package: 1kg-25kg
- Shelf life: 2 years
Functions:
Autophagy inhibitor. Inhibits growth and induces apoptosis of renal cancer cells in vitro. Also inhibits TLR9. Additionally inhibits PRC2 by inhibiting the allosteric binding of PRC2 to EED (embryonic ectoderm development) within the H3K27me3-binding pocket, and reduces H3K27me3 levels in multiple myeloma cells in vitro.
- Hydroxychloroquine is used to treat:
- Rheumatoid arthritis
- Discoid and systemic lupus erythematosus (SLE)
