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Drug Optimization Strategy Equipment & Supplies

2 equipment items found

Alfa - Fluorinated Azaindoles

Alfa - Fluorinated Azaindoles

Manufactured by:Alfa Chemistry   based inNY, NEW YORK (USA)
Azaindoles and their derivatives exhibit significant biological activities, hence they are widely concerned in terms of drug optimization strategies. The four azaindole positional isomers, which associate a pyridine and a pyrrole ring by a fused C-C bond, possess all of the criteria necessary to be excellent bioisosteres of the indole or purine ...
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Alfa - Difluoromethyl Heterocyclic Fluorinated Building Blocks

Alfa - Difluoromethyl Heterocyclic Fluorinated Building Blocks

Manufactured by:Alfa Chemistry   based inNY, NEW YORK (USA)
Introducing fluorine atom(s) into bioactive organic compounds has become a leading strategy for drug design and lead optimization. In drug synthesis strategy, fluorine is frequently employed to modify biologically relevant properties such as metabolic stability, basicity, lipophilicity and bioavailability. ...
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