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Lupus Equipment & Supplies
69 equipment items found
by:Progentec Diagnostics, Inc. based inOklahoma City, OKLAHOMA (USA)
A BIOMARKER BASED TEST TO MEASURE CURRENT DISEASE ACTIVITY. THE AISLE DX DISEASE ACTIVITY TEST SUPPORTS CLINICIANS IN THE MEASUREMENT OF LUPUS (SLE) AND THE ASSESSMENT OF TREATMENTS. BLOOD PLASMA BASED ...
Manufactured by:DxTerity Diagnostics Inc. based inRancho Dominguez, CALIFORNIA (USA)
DxTerity’s IFN-1 Test uses a simple fingerstick blood collection conducted at your doctor's office. Measure your IFN-1 levels and know your risks for SLE disease progression. Take back control of your ...
by:Horizon Therapeutics plc based inSaint Kevin`s, IRELAND
A fully human monoclonal antibody against ILT7 that depletes certain dendritic cells. We are investigating daxdilimab in dermatomyositis, discoid lupus erythematosus and lupus nephritis as well conducting Phase 2 clinical trials in alopecia areata and systemic lupus ...
Manufactured by:D-tek s.a. based inMons, BELGIUM
These autoantibodies are diagnostic markers and classification criteria for Sjögren’s Syndrome. They are also associated with SLE and Subacute Cutaneous Lupus Erythematosus (SCLE) and present in 90 % of patients with Neonatal Lupus Erythematosus (NLE). ...
Manufactured by:D-tek s.a. based inMons, BELGIUM
Following the American College of Rheumatology (ACR), the presence of anti-dsDNA antibodies is one of the diagnostic criteria for Systemic Lupus Erythematosus (SLE). Indeed, they are reported to have a high pathogenic and diagnostic significance for SLE. They are among the most frequently detected autoantibodies associated with SLE. Moreover the dsDNA antibody titer usually ...
Manufactured by:Galapagos NV based inMechelen, BELGIUM
A TYK2 inhibitor for which topline results from the Phase 1b in psoriasis were reported in July 2021. Phase 2 studies in dermatomyositis and Systemic Lupus Erythematosus (SLE) are expected to start in ...
Manufactured by:Galapagos NV based inMechelen, BELGIUM
GSK has all rights to these compounds, and Galapagos is eligible to receive milestones and up to double-digit royalties on global sales. In the course of 2013, GSK initiated Phase 2 studies with GSK2586184 (formerly GLPG0778) in systemic lupus erythematosus, chronic plaque psoriasis, and ulcerative colitis. In February 2014, GSK stopped the lupus study due to a ...
Manufactured by:ORGENTEC Diagnostika GmbH is part of the Sebia Group based inMainz, GERMANY
Regardless of their immunoglobulin class, cardiolipin autoantibodies are an important criterion for the diagnosis of APS. Autoantibodies against cardiolipin are also an immunological classification criterion for systemic lupus erythematosus (SLE). In addition, the quantitative determination of anti-cardiolipin is very useful for monitoring SLE patients with secondary APS. ...
Manufactured by:AROTEC Diagnostics Limited based inWellington, NEW ZEALAND
Autoantibodies directed to negatively charged phospholipids, in particular cardiolipin, have been detected in the serum of patients with systemic lupus erythematosus (SLE) and antiphospholipid syndrome (APS). APS is characterised by venous and arterial thrombosis, recurrent spontaneous abortions and thrombocytopenia. It is now known that a serum cofactor, β2-glycoprotein 1, ...
Manufactured by:ImmunoVision, Inc. based inSpringdale, ARKANSAS (USA)
Use of plasmid DNA in ELISA is an effective method for the detection of anti-double-stranded (ds) DNA antibodies (1). The presence of antibodies to dsDNA is included in the 1982 revised criteria for classification of Systemic Lupus Erythematosus (SLE) ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
PAD-IN-2 can be used in the research of auto-immune diseases and cancers, such as rheumatoid arthritis, vasculitis, systemic lupus erythematosis, cutaneous lupus erythematosis, ulcerative colitis, cystic fibrosis, asthma, multiple sclerosis and ...
Manufactured by:AROTEC Diagnostics Limited based inWellington, NEW ZEALAND
These autoantibodies are also often detected in sera from patients with Raynaud’s phenomenon and occasionally in other rheumatic diseases such as systemic lupus erythematosus, Sjögren’s syndrome, and rheumatoid arthritis. ACA have also been reported to occur with high prevalence in patients with primary biliary cirrhosis, in patients with malignancies and ...
Manufactured by:Erba Mannheim based inLondon, UNITED KINGDOM
This four channel coagulation analyzer redefines the benefits in its class. Erba ECL 412, can perform PT, APTT, Fibrinogen, Thrombin Time , All Factiors, Lupus , Protein S, Protein C , Antithrombin III and DDimer. ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Edecesertib (GS-5718) is a selective, potent, orally active IRAK-4 inhibitor. Edecesertib has anti-inflammatory activity. Edecesertib can be used for rheumatoid arthritis (RA) and lupus erythematosus (LE) ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Dalazatide (ShK-186) is a specific Kv1.3 potassium channel peptide inhibitor. Dalazatide can be used in the study of autoimmune diseases such as multiple sclerosis (MS), lupus erythematosus, psoriasis, rheumatoid arthritis, type 1 diabetes and inflammatory bowel ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Hydroxychloroquine (HCQ) is a synthetic oral antimalarial drug that can be used in the study of malaria and autoimmune diseases such as systemic lupus erythematosus and rheumatoid arthritis. Hydroxychloroquine is a potent autophagic flux inhibitor with antiviral activity (such as SARS-CoV-2 virus) that inhibits Toll-like receptor 7/9 (TLR7/9) ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
RN486 is a potent, selective and orally active Btk inhibitor with an IC50 of 4.0 nM and a Kd of 0.31 nM. RN486 is less active for other kinases. RN486 can be used for rheumatoid arthritis and systemic lupus erythematosus ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
RO5461111 can effectively inhibit the activation of antigen-specific T cells and B cells. RO5461111 can improve pulmonary inflammation and lupus ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
JAK-IN-11 is a potent and selective JAK inhibitor extracted from patent WO2012122452A1, Compound II, has the potential for the skin disorders (such as cutaneous lupus) treatment[1]. JAK-IN-11 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Mefloquine is also a K+ channel (KvQT1/minK) antagonist with an IC50 of ~1 μM. Mefloquine can be used for malaria, systemic lupus erythematosus and cancer ...