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Metabolism Drug Equipment & Supplies
134 equipment items found
Manufactured by:ViennaLab Diagnostics GmbH based inVienna, AUSTRIA
Genetic variants of the drug-metabolizing enzyme CYP2C9 lead to high inter-individual dose response variability of certain drugs, in particular coumarin-based anticoagulants. The CYP2C9 mpx RealFast™ Assay allows for the simultaneous detection of CYP2C9*2 and CYP2C9*3 variants exhibiting impaired enzyme ...
Manufactured by:Oxford Biomedical Research, Inc. based inRochester Hills, MICHIGAN (USA)
This polyclonal antibody to human glutathione S-transferase A1-1 is produced in goat and is provided as an ammonium sulfate ...
Manufactured by:Genabio Diagnostics Inc. based inBedford, MASSACHUSETTS (USA)
Intended use: Wondfo® T-Square Oral Fluid Drug Test is a simple and convenient method of drug screening. Full observation during collection allows the testing to be performed anytime and anywhere, which greatly reduces the specimen-tampered concerns. Because it takes time for drug to metabolize and pass through body, oral ...
Manufactured by:Cytes Biotechnologies based inBarcelona, SPAIN
Hepatic non-parenchymal cells (NPCs) represent about 30% of the liver and are specialized cells which interact with hepatocytes for several functions. For this reason, liver co-cultures may increase the sensitivity of liver models for ADME/Tox-related research by recapitulating the complexity of a whole liver. "Mix NPCs" provides a mix of different types of liver cells, including Kupffer cells, ...
Manufactured by:Ahlstrom based inEspoo, FINLAND
Easy Collection - Reliable and Quantitative Analysis - Design for Automation. Ahlstrom AutoCollect card is designed for dried blood spot (DBS) microvolume sampling, transport and storage at ambient ...
Manufactured by:Allevi, Inc. based inPhiladelphia, PENNSYLVANIA (USA)
Clinically relevant drug-drug interactions (DDI) are a serious concern for any new drug development project. To better support capturing the multiple mechanisms of DDI potential using primary hepatocytes, we now offer Interaction Qualified Human Hepatocytes (Catalog HUCPI) which are characterized for 3 major mechanisms of DDI: transporter activity, enzyme activity, and induction potential, ...
Manufactured by:Puracyp based inCarlsbad, CALIFORNIA (USA)
Puracyp’s nuclear receptor activation kits are all-inclusive cell-based assay systems. The kits incorporate mycoplasm-free, stably-transfected cells derived from hepatoma cell lines that have been treated with a cell-arrest agent to prevent further proliferation. Exposure to the cell-arrest agent ensures that the cells in the kits can only be used for a single 96 well assay. Each kit ...
by:Wondfo USA Co Ltd. based inWillowbrook, ILLINOIS (USA)
SAFElife Oral Fluid Testing is a simple and convenient method of drug screening. Full observation during collection allows the testing to be performed anytime and anywhere, which greatly reduces specimen tamper concerns. Because it takes time for drugs to metabolize and pass through the body, oral fluid is recognized as the optimal ...
Manufactured by:Cytes Biotechnologies based inBarcelona, SPAIN
Acquisition of hepatocyte samples is now a critical step for research activities. The limited availability of human hepatocytes makes cryopreservation a good option to provide researchers with a sufficient amount of viable liver ...
Manufactured by:Cytes Biotechnologies based inBarcelona, SPAIN
Hepatic stellate cells (HSC) are also known as perisinusoidal cells and they are located in the space of disses. These cells are the major cell type involved in liver fibrosis in response to liver injury and they play a key role in the homeostasis of liver extracellular matrix, repair, regeneration and fibrosis, and control retinol metabolism, storage and ...
Manufactured by:Cytes Biotechnologies based inBarcelona, SPAIN
The fresh human hepatocytes we offer are obtained and isolated from human donors for research purposes. These cells are a superior in-vitro model because they thrive in an environment closely resembling the in-vivo host ...
Manufactured by:Quay Pharma based inFlintshire, UNITED KINGDOM
Lipophilic systems have proven effectiveness in improving bioavailability by helping drugs to overcome problems like poor gastric solubilisation, degradation and elimination due to first-pass metabolism in the liver, other types of pre-systemic metabolism, and drug transport and efflux effects. At Quay Pharma, we are highly ...
Manufactured by:LMA Airway Management abrand of Teleflex Incorporated based inAthlone, IRELAND
The unique design of MAD Nasal™ enables a seal to be formed with the nostril and atomized particles of medication to be delivered to the nasal mucosa. The particles are then absorbed through the mucosal tissue and into the bloodstream, avoiding first pass metabolism. ...
Manufactured by:Lumen Bioscience, Inc. based inSeattle, WASHINGTON (USA)
Cardiometabolic disease (CMD)—a cluster of related conditions that includes obesity, diabetes, and cardiovascular disease—afflicts hundreds of millions of people worldwide, and the associated health and economic burdens continue to grow. An estimated 17.9 million people died from CMD in 2019, representing nearly a third of all global deaths. Of these deaths, 85% were due to heart ...
by:Lena Biosciences, Inc. based inAtlanta, GEORGIA (US) (USA)
n vivo, over 98% of oxygen delivery to tissues and cells is delivered by hemoglobin contained in the red blood cells. Lena Biosciences Blood Substitute is the first, screening compliant product that solves the problem of poor cellular oxygenation leading to ischemia, necrosis, de-differentiation, and transcriptional drift that cells experience in vitro. Learn how our synthetic hemoglobin analog ...
Manufactured by:Cytes Biotechnologies based inBarcelona, SPAIN
Primary animal hepatocytes and subcellular liver fractions (Microsomes, Cytosol and S9 fraction) are model systems often used for a variety of in vitro screenings and analyses prior to clinical studies in human and animal health as well as environmental toxicology. Hepatocytes in suspension are preferable for short-term studies whereas plated hepatocytes are more useful for long-term ...
Manufactured by:CML Biotech (P) Ltd. based inErnakulam Dist., INDIA
Centrifuge at 2000-3000 rpm for 10 min. at room temperature. Used for emergency Biochemistry test, Endocrine and metabolic disorders, Therapeutic Drug monitoring and Toxicology, Electrolytes, Clinical chemistry, Serology and immunology etc. Lithium test should not be performed using Lithium Heparin tubes. ...
by:Lena Biosciences, Inc. based inAtlanta, GEORGIA (US) (USA)
Lena Biosciences offers a robust 3D cell culture system for routine, predictive testing in vitro. SeedEZ is a three-dimensional cell culture scaffold made of randomly oriented, inert glass microfibers. The diameter of microfibers is carefully optimized for long-term cell growth and repeat-dose drug testing. The microfibers are arranged in such a way that creates tiny pores for nutrients, gases, ...
Manufactured by:CML Biotech (P) Ltd. based inErnakulam Dist., INDIA
Gently invert the tubes 180° 5-8 times immediately after blood collection or mix using roller mixer. Used for emergency Biochemistry test, but also for Endocrine and metabolic disorders, Therapeutic Drug monitoring and Toxicology, Electrolytes, Clinical chemistry, Serology and immunology etc. Centrifuge at 2000-3000 rpm for 10 min. at room temperature. ...
by:Oncodesign based inDijon, FRANCE
Oncodesign’s Pharmimage® technology module is a pharmaco-imaging module designed to monitor the effect of treatments and to define effective translational biomarkers in precision medicine. It includes translational, optical (bioluminescence, fluorescence), functional and molecular (MRI, PET, SPECT, CT scanner, MRI/PET coupling) multi-modal imaging capabilities, adapted to small rodents ...