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Model SENTI-301 - Multi-Armed Allogeneic CAR-NK Cell Therapy for HCC

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The product profile of SENTI-301 has the potential to promote expansion and persistence of NK cells, and activate and recruit the body’s own immune cells into the solid tumor microenvironment for enhanced anti-tumor activity.

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Pursuing an Unmet Need in the Treatment of HCC

SENTI-301 is designed to target glypican 3, or GPC3, which is highly expressed in 70% to 90% of hepatocellular carcinoma (HCC) cases. Our vision is a potential medicine that enhances anti-tumor activity.