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Natural Killer Cell Equipment & Supplies
112 equipment items found
by:Chimeric Therapeutics based inCarlton South, AUSTRALIA
The CORE-NK platform is a transformative platform technology for Chimeric enabling the accelerated development of multiple next generation, off the shelf NK and CAR-NK products. Natural killer cells are found in our bodies naturally and are able to recognize and kill cancer cells – but are not robust and ...
Manufactured by:Nkarta, Inc. based inSouth San Francisco, CALIFORNIA (USA)
Cell therapy, a new approach that uses immune cells to attack tumors, has emerged as one of the most promising breakthroughs in cancer treatment. First generation approaches have focused on T-cells, which have shown great promise in hematologic malignancies but are plagued with unwanted side effects and, to date, have not shown similar activity in solid tumors. Nkarta was founded to address these ...
by:Chimeric Therapeutics based inCarlton South, AUSTRALIA
The next generation CORE-NK platform will integrate additional activation and expansion features to further optimize the cancer-fighting power of the CORE-NK platform cells. Development of the next generation CORE-NK platform will be as a combination therapy for blood ...
Manufactured by:Ativa Medical based inShoreview, MINNESOTA (USA)
Ativa's Diagnostic Workstation with a miniaturized flow-cytometer can measure the innate immune response cells in the blood. In COVID-19, Natural-Killer Cell activation occurs within hours of first infection, these cells fight the Virus in the lungs. Miniaturized low-cost diagnostic tests Immediate lab-quality ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Amivantamab inhibits ligand binding, promotes endocytosis and degradation of receptor-antibody complexes, and induces Fc-dependent cytokinesis in macrophages and antibody-dependent cytotoxicity in natural killer ...
by:Chimeric Therapeutics based inCarlton South, AUSTRALIA
CHM 1301 (CLTX CAR NK) will be developed on the next generation CORE-NK platform leveraging our CLTX Chimeric Antigen ...
by:Chimeric Therapeutics based inCarlton South, AUSTRALIA
CHM 3301 (Undisclosed CAR NK) will be developed on the next generation CORE-NK platform leveraging a currently undisclosed Chimeric Antigen ...
by:Chimeric Therapeutics based inCarlton South, AUSTRALIA
CHM 2301 (CDH17 CAR NK) will be developed on the next generation CORE-NK platform leveraging our CDH17 Chimeric Antigen ...
by:BlueSky Immunotherapies GmbH based inWien, AUSTRIA
The high level of interferon induced by the delNS vector activates immunological defence reactions against cancer. It also stimulates the production of antiviral ...
Manufactured by:Celyad Oncology based inMont-Saint-Guibert, BELGIUM
CYAD-101 is an investigational, non-gene edited allogeneic (from healthy donor derived) CAR T candidate engineered to co-express the chimeric antigen receptor based on NKG2D, a receptor expressed on natural killer (NK) cells that binds to eight stress-induced ligands (NKG2DL) expressed by a broad range of tumor cells and the ...
Manufactured by:multimmune GmbH based inMunich, GERMANY
ENKASTIM is based on the activation of immune cells called natural killer (NK) cells that are major players in the body's first line of defense, also called innate immunity. The immune effector cells are activated ex vivo (outside the body; ENKASTIM-ev) or in vivo (inside the body; ...
Manufactured by:multimmune GmbH based inMunich, GERMANY
In vivo application of ENKASTIM-iv, an Hsp70-based GMP-grade synthetic peptide comprising 14 amino acids (14mer), results in a specific activation of NK cells which acquire the capacity to recognise and kill membrane Hsp70-positive tumors and ...
Manufactured by:Affimed GmbH based inHeidelberg, GERMANY
The proprietary ROCK platform enables a tumor-targeted approach that can be tailored across hematological and solid tumors. The ROCK (Redirected Optimized Cell Killing) platform allows for a modular approach to generating customizable ICE (innate cell engager) molecules. High-affinity ICE (innate cell engager) molecules, which are created using the ROCK platform, are capable of bivalent NK-cell ...
Manufactured by:Universal Cells Inc. based inSeattle, WASHINGTON (USA)
Class I molecules present peptides to CD8+ T cells and are composed of B2M paired with diverse heavy alpha chains. Human cells express two alleles each of three polymorphic HLA class I molecules (A,B and C) that must be matched to recipients, as well as the non-polymorphic HLA-E molecule. Universal Donor Cells do not express free B2M and lack surface expression of HLA-A, B and C. The B2M-HLA-E ...
Manufactured by:DIAGNOSTIC BIOSYSTEMS INC. based inPleasanton, CALIFORNIA (USA)
CD7 is expressed by most peripheral blood T cells, NK cells, and all thymocytes. It is one of the earliest surface antigens on T and NK-cell lineages. The antibody is a useful aid for classification of T-cell malignancies ...
Manufactured by:Senti Biosciences based inSouth San Francisco, CALIFORNIA (USA)
Pursuing an Unmet Need in the Treatment of CRC - SENTI-401 is designed to more precisely target and eliminate colorectal cancer (CRC) cells while sparing healthy cells elsewhere in the body. Our vision is a potential medicine that more effectively treats patients with colorectal ...
by:Zymeworks Inc based inVancouver, BRITISH COLUMBIA (CANADA)
using precise antibody Fc modifications that tailor the antibody-mediated immune response. Get the optimal response. Tailor immune system response for a desired therapeutic effect using the Effector Function Enhancement and Control Technology’s (EFECT™) library of Fc region modifications. The EFECT™ library includes proprietary mutations to the CH2 domain of the antibody's Fc ...
Manufactured by:Elabscience based inHouston, TEXAS (USA)
CD3, also known as T3, is a member of the Ig superfamily and primarily expressed on T cells, NK-T cells, and at different levels on thymocytes during T cell differentiation. CD3 is composed of CD3ε, δ, γ and ζ chains. It forms a TCR complex by associating with TCR α/β or γ/δ chains. CD3 plays a critical role in TCR signal transduction, T cell ...
Manufactured by:Nkarta, Inc. based inSouth San Francisco, CALIFORNIA (USA)
OX40 costimulatory domain, CD3ζ signaling moiety, membrane bound ...
Manufactured by:Senti Biosciences based inSouth San Francisco, CALIFORNIA (USA)
The product profile of SENTI-301 has the potential to promote expansion and persistence of NK cells, and activate and recruit the body’s own immune cells into the solid tumor microenvironment for enhanced anti-tumor activity. ...