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Celemics - Model NGS - Targeted Enrichment Panel
“Unlike Whole Genome Sequencing, Targeted Sequencing is a technique that selectively analyzes specific regional sequences of genomes.” Our Target Enrichment Panel uses hybridization-based capture technology to enable the core process of Target Sequencing, which is the separation and analysis of specific regional sequences of entire genomes. It can also accurately analyze all types of mutations, such as SNV, InDel, CNV, and Rearrangement.
- Targeted DNA/RNA sequencing
- Germline, somatic mutation analysis
- Liquid biopsy analysis (ctDNA)
- Multiple gene expression analysis
- High-throughput genotyping
- Integration-site sequencing
Celemics’ Target Enrichment Panel utilizes our intrinsic probe design, rebalancing, and molecular barcode technologies to efficiently analyze not only hard-to-capture areas such as GC-rich and homologous regions but also tiny amounts of damaged DNA or RNA originated from circulating tumor cells or FFPE samples.
- Probe design technology
- Rebalancing & Molecular barcode technology
- Analysis of GC-rich and homologous regions
- Minuscule amounts of DNA and RNA analysis
Industry-leading capture performance
Industry-leading on-target ratio, coverage and uniformity
High performance, even in areas difficuz
While other companies purposely mask hard-to-capture areas such as GC-rich and homologous regions, making important mutation analysis difficult, Celemics uses our proprietary technology to guarantee excellent capture capabilities, even in these areas.
Extremely small amounts of damaged
DNA/RNA applicable
Accurate analysis possible with amounts as small as 20ng
High performance even with damaged samples such as FFPE and cfDNA
Pre-capture pooling applicable
Capable of analyzing several sample libraries through one capture by attaching sample indices beforehand when creating libraries, significantly decreasing experimental hands-on time and cost.
Provision of molecular barcode kits and bioinformatics
Provision of molecular barcode kit specifically developed to detect mutations in samples with minuscule amounts, such as cfDNA and bioinformatics algorithm that eliminates duplicates and generates consensus sequences
Gene Add-on service for expending the panels
Decrease of novel panel development time and cost through the addition of newly discovered genes or general panel expansion to already existing client panels
Compatible with all NGS Equipment
Compatible with all NGS devices from Illumina, Thermo Fisher Scientific, Pacific Bioscience and MGI
Support of enzymatic DNA fragmentation
Enabling of experimentation without specific gDNA shearing equipment through the support of ultrasonic-based mechanical shearing and enzymatic fragmentation
Bioinformatics SW provision
Provision of bioinformatics SW that processes raw NGS data (FASTQ) to identify characteristics such as mutation type, VAF and pathogenicity for customer’s convenience
Real QC of all customized panels
Celemics is the only company to provide detailed QC information for all wet-lab experiments, NGS runs and bioinformatics using standard DNA samples when developing Customized Panels
High, uniform lot quality for repeated orders
Provision of customized panels of equally high quality to clients making subsequent orders using proprietary 2-step mass production technology