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Dna Target Equipment & Supplies
39 equipment items found
Manufactured by:LGC SeraCare based inMilford, MASSACHUSETTS (USA)
The Seraseq Tumor Mutation DNA Mix v2 (AF7) HC is a multiplexed mixture of actionable biosynthetic DNA targets precisely blended with a single, well-characterized genomic background. This product is produced under rigorous design control and manufacturing practices to an allelic frequency of 7%, and is offered in a high concentration (HC) format ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
XR5944 is an anti-tumor compound with DNA-targeting activity. As a topoisomerase inhibitor, XR5944 can effectively inhibit the activities of topoisomerase I and II. XR5944 shows excellent anti-tumor activity against human and mouse tumor cells in vitro and in vivo. XR5944 exhibits significant potency in multiple cell lines, with IC50 values of 0.04-0.4 nM. ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
XR5944 is an anti-tumor compound with DNA-targeting activity. As a topoisomerase inhibitor, XR5944 can effectively inhibit the activities of topoisomerase I and II. XR5944 shows excellent anti-tumor activity against human and mouse tumor cells in vitro and in vivo. XR5944 exhibits significant potency in multiple cell lines, with IC50 values of 0.04-0.4 nM. ...
Manufactured by:Massive Photonics GmbH based inMünchen, GERMANY
The MASSIVE-sdAB 1-PLEX Kit from Massive Photonics is designed for DNA-PAINT imaging applications, providing a camelid single-domain antibody (sdAB) to target mouse IgG kappa light chain or rabbit IgG. Engineered for precision, the sdAB is site-specifically coupled to a DNA-PAINT docking site, allowing for improved binding efficiency. ...
Manufactured by:Massive Photonics GmbH based inMünchen, GERMANY
The Primary Antibody Labeling Kit from Massive Photonics is designed for advanced FAST DNA-PAINT imaging, specifically targeting mouse IgG kappa light chain or rabbit IgG primary antibodies. This kit leverages camelid single-domain antibodies (sdABs) coupled to DNA-PAINT sites optimized for rapid imaging and high signal-to-noise ratios. ...
by:Linear Diagnostics Limited based inBirmingham, UNITED KINGDOM
Our patented linear dichroism and EXPAR technology have a number of distinct advantages including very rapid and accurate results, as well as the ability to detect multiple targets simultaneously.Linear dichroism works by detecting a shift in the plane of polarised light when a target is bound to a detector. Different molecular recognition methods can be used on ...
Manufactured by:Fusion Genomics Corporation based inBurnaby, BRITISH COLUMBIA (CANADA)
QUANTUMProbes, the second component of our ONETest molecular diagnostics assay kit, are comprised of synthetic non-reference based oligonucleotides designed using Fusion Genomics’ machine learning algorithms. ...
Manufactured by:Panagene Inc. based inDaejeon, SOUTH KOREA
HPV is well-known as as major cause of cervical cancer. More than 40 pathogens in 100 kinds of HPV has been found in female genital organ. The High-Risk group of those viruses is generally known for a direct correlation with cervical cancer. That is why WHO highly recommend the HPV DNA test. PANA RealTyper™ HPV Kit can detect 14 pathogens of High risk group and 2 pathogens of Low risk ...
Manufactured by:Locus Biosciences, Inc. based inMorrisville, NORTH CAROLINA (USA)
CRISPR evolved as a bacterial immune system, which protects bacterial cells from invading viruses. Cas3 is a powerful exonuclease that shreds the DNA of targeted bacterial cells beyond repair, leading to rapid and predictable cell death. We use Cas3 to dramatically increase the potency of crPhage compared to their natural phage counterparts where we ensure that ...
Manufactured by:INOVIO Pharmaceuticals based inPlymouth Meeting, PENNSYLVANIA (USA)
INOVIO’s DNA medicines are made using a process called SynCon®. SynCon uses a proprietary computer algorithm that has been designed to identify and optimize the DNA sequence of the target antigen, whether it is a virus or a tumor. Once this sequence has been determined, the DNA is synthesized or reorganized, and ...
by:Eligo Bioscience based inParis, FRANCE
Eligobiotics are a first-in-class proprietary modality that enables the delivery and expression of therapeutic DNA in target bacterial populations of the microbiome. This technology allows modulation of the microbiome’s composition and function to address human disease with an unprecedented ...
Manufactured by:Panagene Inc. based inDaejeon, SOUTH KOREA
Mutations of IDH1 (isocitrate dehydrogenase 1,IDH1) can be found in glioblastoma and myeloproliferative neoplasm. Detection of IDH1mutations can be a positive predictor of a prognosis and a molecular marker for glioblastoma patients. On the other hand, it is reported that IDH1 mutations correlate with poor prognosis in myeloproliferative neoplasm. PNAClamp™ IDH1 Mutation Detection Kit is a ...
Manufactured by:Panagene Inc. based inDaejeon, SOUTH KOREA
BRAF mutation is found in several cancers including thyroid cancer, malignant melanoma, ovarian cancer, colorectal cancer. In case of thyroid cancer, there are over 40 different types of BRAF mutation. Of these mutations, the V600E mutation on exon 15, i.e. change of nucleotide from T to A in 1799th base that results in change from valine to glutamate in amino acids, is most important with over ...
Manufactured by:Solis BioDyne based inTartu, ESTONIA
Dye-based real-time quantitative PCR (qPCR) uses DNA binding dye to evaluate the DNA amplification process during PCR. In this mix EvaGreen® double-stranded DNA binding dye is used instead of the more widely used SYBR Green I that has similar fluorescence spectra. Compared to SYBR Green I dye EvaGreen® dye shows a higher fluorescence level, high sensitivity for detecting low template ...
Manufactured by:Panagene Inc. based inDaejeon, SOUTH KOREA
NRAS mutation is found in several cancers such as melanoma (13~25%), colorectal cancer (1~6%), lung cancer (1%), thyroid cancer (7%) and hepatocellular carcinoma (10%). It is know that the drug response against colorectal cancer medicine such as Erbitux and Cetuximab decreased and the prognosis of the metastatic colorectal cancer patient is bad if the patient has NRAS mutation. Recently, there ...
Manufactured by:Panagene Inc. based inDaejeon, SOUTH KOREA
According to the WHO report (2008), human papillomavirus (HPV) causes virtually 100% of cases of cervical cancers. There are more than 100 genotypes of HPV reported currently, and HPV consists of double helix circular DNA with ca. 7,900 bps. Compared to the traditional Pap smear test, HPV genotyping has several advantages; 1) high accuracy of determining existence of HPV viruses, 2) genotyping of ...
Manufactured by:BioChek BV based inReeuwijk, NETHERLANDS
A highly sensitive and specific PCR test kit allowing simultaneous differentiation and quantification of Campylobacter Coli, Campylobacter Jejuni and/or Campylobacter Lari DNA, extracted from primary production, production environment, and food samples, including sample ...
Manufactured by:ZenTech s.a. based inLiège, BELGIUM
The Targeted qPCR SMA uses the quantitative polymerase chain reaction to genotype the anterior spinal muscular atrophy (SMA) mutation in neonates on a dried blood sample. The test only identifies SMA homozygotes. This qualitative test is dedicated only to spinal muscular atrophy (SMA) newborn screening and is performed on a dried blood sample on 903® or 226 blotted paper. Parameter ; ...
Manufactured by:Amoy Diagnostics Co., Ltd. based inXiamen, CHINA
The phosphoinositide-3 -kinase catalytic alpha (PIK3CA) gene produces the p110 alpha (pl 10a) protein, which is one subunit of an enzyme called phosphatidylinositol 3-kinase (PI3K). PI3K plays a key role ofPI3K/Akt signaling pathway in numerous cellular processes critical for cancer progression, including metabolism, growth, survival, and motility. Somatic mutations in the PIK3CA gene are found ...
Manufactured by:Fluxergy based inIrvine, CALIFORNIA (USA)
Simple Molecular Testing and More at Your Practice. Fluxergy provides a solution that eliminates the Friday dilemma of waiting for lab results on the weekend. Design and build PCR tests at your practice that give you results within 1 ...