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Dna Target Articles & Analysis
12 news found
The field of protein DNA/RNA interactions is an expanding area of research. These interactions affect fundamental processes and as a result, relevant protein DNA/RNA processing complexes and their associated mechanisms provide interesting therapeutic targets to researchers. ...
Focusing on a cohort of advanced & refractory cancer patients without tractable DNA alterations, the analysis concludes that the AI-transcriptional-based therapeutic recommendation-tool Onco KEM® is feasible and has the potential to identify potential therapeutic options for personalized cancer treatment. The study included the analysis of 50 patients who had no ...
Yoh Matsumoto from the Immunotherapy Development Inc. in Saitama, Japan and the Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan. The AD Vaccine, YM7555, is a DNA Vaccine that targets both ABeta and TAU, which accumulate and are necessary for the development of AD. ...
ViGeneron announces follow-on collaboration with Daiichi Sankyo to develop a novel gene therapy for prevalent eye diseases The companies agree a follow-on collaboration to evaluate ViGeneron’s adeno-associated virus vectors (vgAAVs) for delivering Daiichi Sankyo’s novel therapeutic protein to treat prevalent eye diseases ViGeneron GmbH, a next-generation gene therapy company, ...
HRD represents a disruption to the normal cellular pathway that repairs double-stranded DNA breaks, which consequentially results in acquired chromosomal breakage. Clinical research has shown that cells with HRD are more sensitive to certain therapies, like Poly(ADP-Ribose) Polymerase (PARP) inhibitors and other DNA repair-targeting drugs; ...
Eligo Bioscience SA, a Paris, France-based microbiome engineering company, today announced that the Company presented preclinical data on its lead drug candidate, EB003, for the treatment of severe diarrhea induced by shiga-toxin (Stx) producing E. coli (STEC, leading to Hemolytic Uremic Syndrome), at the 14th Annual CRISPR 2021 meeting held June 1-10, 2021. The data presented further supports ...
Transposition works through a “cut-and-paste” mechanism, where the Tn5 excises itself from the donor DNA and inserts into a target sequence, creating a 9-bp duplication of the target. DNA transposition is a useful model that can be used to understand the interaction of other types of proteins with ...
The new panel enables simultaneous analysis of DNA mutations and RNA fusion transcripts in myeloid samples in a single day. It also provides researchers the ability to profile 40 DNA targets and 29 fusion driver genes, enabling detection of more than 600 fusion isotypes to identify biomarkers associated with myeloproliferative neoplasm (MPN), ...
Each cell’s development, reproduction and death are controlled by the instructions contained in DNA. The History of DNA Sequencing In the 1970s, the first DNA sequences were obtained by academic researching using slow, labor-intense methods. ...
(NYSE: A) today introduced the new SureDirect Blood PCR Kit for amplification of DNA directly from blood and blood derivatives, without the need for nucleic acid extraction and isolation. ...
(NYSE: A) today introduced a new SureSelect target enrichment solution that allows Ion Proton users to realize the full power of their next-generation sequencers with the industry's leading human exome and custom DNA target enrichment solutions. SureSelect target enrichment is now available for all major sequencing platforms, ...
We're confident that researching novel therapeutic targets such as oncogenic fusions will help facilitate development of personalized medicine for other cancers as well." ...