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Khymeia Group
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Model Neurowave - The Most Advanced System for Coma And Minimum Consciousness State

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Neurowave is an innovative “open” and extremely flexible technological platform aimed at clinical applications, including experimental ones, in the context of Serious Disorders of Consciousness – Vegetative and Minimum Consciousness States – during all phases of the patient’s journey. Neurowave brings together and includes all the system functions in a single chassis that is placed on the patient’s bed while maintaining minimum dimensions even in sensitive environments such as intensive care. The system can be easily moved from one bed to another, thus benefiting from the many features for multiple patients.
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Neurowave is the most innovative system for searching for any active patient / environment communication channels. The system allows the delivery of a large dataset of stimuli, including patient specific ones relating to the emotional sphere, which can also be loaded in real time and remotely. Simultaneously with the delivery of stimuli, the system allows recording of the appropriate neurophysiological parameters in order to verify any possible correlations between stimuli and acquired recordings. Neurowave delivers both consolidated standard and experimental and patient-specific protocols, allowing to program with extreme simplicity and flexibility the time-line for managing stimuli, acquisitions and analyzes, creating models and protocols based on known or innovative paradigms for rehabilitation stimulation multisensory.

Neurowave is the innovative clinical and research tool integrated for: - Biophysiological monitoring of the acute patient with identification of communication channels - Clinical investigations on acute patients in resuscitation wards through the Visual Evoked Potentials from Flash and Pattern, aimed at verification and quantification of responses to cognitive evoked potentials (PECs) such as MMN, P300, N400 - Clinical investigations on post-acute patient in a vegetative state and a state of minimal consciousness at the level of quantitative EEG and at the level of Cognitive Evoked Potentials at non-structured sensory stimulations (still) conventional, such as investigations with audio / video stimuli with emotional content - Programming and implementation of patient sensory stimulation sessions, for the creation of models and protocols based on paradigms (known or innovative) for multisensory rehabilitation stimulation and evaluation of any synergies between different modalities of stimulation

The module used for the Minimal Conscious State allows to administer to the patient in a vegetative state and a state of minimal consciousness, a wide range of stimulations while simultaneously recording a complete series of neurophysiological signals. It therefore provides a complete system for verifying any correlations between sensory stimulations and changes in the patient`s status, which can be measured by quantitative analysis of physiological and neurophysiological parameters.