MtoZ Biolabs - Model diabetes-mellitus - Diabetes Mellitus Analysis Service
Diabetes is marked by hyperglycemia, resulting from defects in insulin secretion and action, which disturbs the metabolism of carbohydrates, fats, and proteins. Type 1 diabetes (T1D) is an autoimmune disease where T cells mediate inflammation and specifically damage pancreatic β cells. Cytokines produced by macrophages and lymphocytes in the islets, such as IL-1β, TNF-α, IFN-α/γ, play critical roles in regulating T cell activation and population, as well as the immune response to and destruction of β cells, crucial to the development and progression of T1D.
Kaur, K. K. et al.J. Endocrinol.2017.
MtoZ Biolabs employs flow cytometry for the simultaneous quantification of diabetes-related cytokines and proteins, providing higher sensitivity and a wider detection range. The following table includes cytokines detectable in human samples, with services also available for other species.
1. A Minimum of 25 µL of Sample is Required, Compared to the 50 µL or 100 µL Needed for Conventional ELISA
2. Applicable to Serum, Plasma, Cell Culture Supernatants, and Various Bodily Fluids
3. Bodily Fluid Samples must be Stored at -80 ℃ and Shipped with Dry Ice
In the technical report, MtoZ Biolabs will provide you with detailed technical information, including:
1. Experimental Procedures
2. Raw Data (Fluorescence Emission Spectra)
3. Technical Report
4. Absolute Content of Each Test Indicator (Excel Spreadsheet)
MtoZ Biolabs is an integrate contract research organization (CRO) providing advanced proteomics, metabolomics, bioinformatics, and biopharmaceutical analysis services to researchers in biochemistry, biotechnology, and biopharmaceutical fields. The name of MtoZ represents “mass to charge ratio” in mass spectrometry analysis, as most of our services are provided based on our well-established mass spectrometry platforms. Our services allow for the rapid and efficient development of research projects, including protein analysis, proteomics, and metabolomics programs.
MtoZ Biolabs is specialized in quantitative multiplexed proteomics and metabolomics applications through the establishment of state-of-the-art mass spectrometry platforms, coupled with high-performance liquid chromatography technology. We are committed to developing efficient, and effective tools for addressing core bioinformatics problems. With a continuing focus on quality, MtoZ Biolabs is well equipped to help you with your needs in proteomics, metabolomics, bioinformatics, and biopharmaceutical research. Our ultimate aim is to provide more rapid, high-throughput, and cost-effective analysis, with exceptional data quality and minimal sample.
Email: marketing@mtoz-biolabs.com