Refine by
Cytokine Detection Services
9 services found
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Cell death occurs through several pathways including apoptosis, necrosis, and other emergent pathways. Apoptosis is pivotal in immune responses, involving processes such as intracellular balance, T cell clustering, the death of reactive lymphocytes, and cytotoxity of target cells. Apoptosis involves key components like APO-1/Fas, a receptor essential for apoptotic signaling; Caspase-3, crucial ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Metabolic bone disease encompasses a range of bone disorders caused by congenital or acquired factors that disrupt normal bone metabolism and biochemical states, leading to disorders in bone biochemistry and metabolism. These disorders stem from abnormalities in three key areas: bone resorption, bone growth, and mineral deposition. Increasingly, research has identified numerous cytokines involved ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
During the tumor formation process, cancer cells release various cytokines and growth factors into the surroundings and reprogram many other types of cells to establish a tumor microenvironment. As a result, tumor tissues almost always contain a large number of endothelial cells, fibroblasts, and infiltrating inflammatory cells, which in turn produce various cytokines. Tumor-derived VEGF acts on ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Cardiovascular diseases are usually associated with systemic inflammatory responses, such as increased expression of inflammatory proteins CRP, IL-1, IL-6, IL-18, and TNF-α. These proteins can be considered as diagnostic markers for the risk assessment of various cardiovascular diseases. For instance, CD40, which belongs to the tumor necrosis factor receptor superfamily, and CD40L play a crucial ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Systemic lupus erythematosus (SLE) is a classic systemic autoimmune disorder characterized by impaired autoimmune tolerance and high concentration of autoantibodies targeting self-antigens, which lead to organ damage. This pathological process involves multiple cytokines. ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Atopic Dermatitis (AD) is prevalent among children aged 1 to 5 years and a considerable number of patients carry this condition into adulthood. As a chronic inflammatory skin disease, AD often coexists with asthma and rhinitis. At the cellular level, the hallmark of AD is characterized by high serum IgE levels, where T cells play a crucial regulatory role. ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Obesity is a systemic disease, not only does it lead to changes in body shape, but it also brings along various diseases and complications, affecting an individual's overall health. Common complications, such as hyperglycemia, hyperlipidemia, and hypertension, are medically termed as "metabolic syndrome". The fluid factors secreted by adipose tissue propel the development of metabolic syndrome ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
To maintain the immune system's homeostasis, multiple control systems are essential for managing infections, inhibiting tumor growth, preventing inflammation, and avoiding autoimmune diseases. T cells are known to be critical in this regulatory process. Specifically, Th3 cells primarily secrete TGF-β along with varying levels of IL-4 and IL-10. Natural regulatory T cells and Tr1 cells can ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Diabetes is marked by hyperglycemia, resulting from defects in insulin secretion and action, which disturbs the metabolism of carbohydrates, fats, and proteins. Type 1 Diabetes (T1D) is an autoimmune disease where T cells mediate inflammation and specifically damage pancreatic β ...