Alfa Chemistry - Dominant Skeleton Discovery and Screening

In chemical concepts, dominant skeleton refers to the core structure of small molecules. In computational chemistry and medicinal chemistry, the skeleton also has the same meaning. The discovery of active compounds with novel skelecton is a great challenge for modern medicinal chemistry. It can not only improve the efficacy and drug-like properties of molecules, but also help pharmaceutical companies break patent barriers and build core competitiveness. Skeleton transition is a commonly used strategy for exploring novel skeleton, which usually starts from known compounds to find compounds with similar activities but with different core structures. Learn more at https://wavefunction.alfa-chemistry.com/services/dominant-skeleton-discovery-and-screening.html