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Drug Molecule Services

47 services found

MtoZ Biolabs - Small Molecule Drug Screening Service-Receptor Categories

MtoZ Biolabs - Small Molecule Drug Screening Service-Receptor Categories

by:MtoZ Biolabs   based in, MASSACHUSETTS (USA)
Receptors are biomolecules that can bind with hormones, neurotransmitters, drugs, or intracellular signaling molecules and are capable of inducing changes in cellular function. Receptors are categorized based on their cellular location into cell surface receptors and intracellular receptors. Each receptor typically has two active sites: one that recognizes and ...
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CD Formulation - Preparation of Nano-vesicles for Encapsulating Protein Drugs

CD Formulation - Preparation of Nano-vesicles for Encapsulating Protein Drugs

Manufactured by:CD Formulation   based in, NEW YORK (USA)
Preparation of Nano-vesicles for Encapsulating Protein Drugs: CD Formulation can customize the vesicles that encapsulate protein drug molecules to avoid the technical problems of drug rupture and leakage during in vivo delivery. Our technical team will perform a full range of analytical tests to ensure that the product meets your ...
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CD Formulation - Stability Analysis

CD Formulation - Stability Analysis

Manufactured by:CD Formulation   based in, NEW YORK (USA)
Under the influence of various environmental factors (such as temperature, humidity, and light), the stability of active pharmaceutical ingredients (API) or the stability of pharmaceutical products is evaluated. This is helpful to study the internal stability of candidate drug molecules and obtain useful information, it is important to improve the integrity of ...
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CD Formulation - Liposome Drug Delivery Technology

CD Formulation - Liposome Drug Delivery Technology

Manufactured by:CD Formulation   based in, NEW YORK (USA)
Liposomes are a novel drug delivery system; they are bimolecular vesicle structures that form spontaneously when phospholipids are dispersed in water. Liposomes vary in size, composition and charge and serve as carriers for a wide range of drug molecules, such as chemotherapeutic agents, anti-microbial and viral drugs, ...
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Cross Species Comparison Services

Cross Species Comparison Services

Manufactured by:Newcells Biotech Limited   based inNewcastle Upon Tyne, UNITED KINGDOM
Cross-species comparison of drug handling with near-physiological kidney transporter model. New drug molecules are usually tested in vivo in two preclinical species to gain a more detailed understanding of how they are transported and eliminated through the kidney and also to mitigate risk of renal toxicity in humans. ...
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Haematology for Novel Drug Concepts for Blood Diseases

Haematology for Novel Drug Concepts for Blood Diseases

Manufactured by:Kiadis Pharma NV   based inAmsterdam, NETHERLANDS
Our efforts in haematology are currently focussed on non-malignant blood disorders including forms of anaemia. Our approach is to identify functional and developable lead molecules and quickly proceed to verified animal disease models to study the direct impact of our drug candidates with clinically relevant read outs. We build our know-how by working on common ...
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MtoZ Biolabs - Protein Active Component Identification and Quantification

MtoZ Biolabs - Protein Active Component Identification and Quantification

by:MtoZ Biolabs   based in, MASSACHUSETTS (USA)
Protein-based macromolecular drugs, typically organic compounds with molecular weights exceeding 1000, depend on cellular biosynthesis and are also known as biologics. Compared to traditional small molecule drugs, protein drugs are characterized by their high potency, strong specificity, low toxicity, clear biological function, ...
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Alfa Chemistry - Dominant Skeleton Discovery and Screening

Alfa Chemistry - Dominant Skeleton Discovery and Screening

Manufactured by:Alfa Chemistry   based inNY, NEW YORK (USA)
In chemical concepts, dominant skeleton refers to the core structure of small molecules. In computational chemistry and medicinal chemistry, the skeleton also has the same meaning. The discovery of active compounds with novel skelecton is a great challenge for modern medicinal chemistry. It can not only improve the efficacy and drug-like properties of ...
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CrypticScout - Mixed Solvent Molecular Dynamics For Drug Discovery

CrypticScout - Mixed Solvent Molecular Dynamics For Drug Discovery

by:Acellera   based inStanmore, UNITED KINGDOM
This protocol simulates the target of interest (GPCR, kinase, ion channel, etc.) in a solution of water and a co-solvent, like benzene or any other fragment-like molecule. During the simulation, the co-solvent molecules interact with the surface of the protein, revealing binding hotspots. These hotspots have been proven to correlate very well with actual pockets. ...
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Alfa Chemistry - Property Prediction of Drug-like Molecules

Alfa Chemistry - Property Prediction of Drug-like Molecules

Manufactured by:Alfa Chemistry   based inNY, NEW YORK (USA)
The Alfa Chemistry platform integrates predictive methods with various computational techniques to accelerate drug discovery. Our iterative process is designed to accelerate evaluation and optimization of chemical matter in silico ahead of synthesis and assay. The most promising compounds emerging from each round of experimental project chemistry are then further optimized through additional ...
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Route Scouting Services

Route Scouting Services

by:Patheon Inc.   based inDurham, NORTH CAROLINA (USA)
Establishing the best synthetic route for your molecule is the basis for a reliable supply throughout the product’s life cycle. During route scouting, the following considerations are important when selecting the optimal pathway: Safety, Efficiency, purity and costs, Ease of optimization and scale up, IP review, Security of supply of raw materials, Impact on waste and the ...
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CD Formulation - Microsphere Development

CD Formulation - Microsphere Development

Manufactured by:CD Formulation   based in, NEW YORK (USA)
Microsphere Development: Among the many existing extended release formulations, microspheres have unique advantages such as gradual release of the drug by degradation of the microspheres after administration, avoidance of blood concentration peaks and valleys, reduction of the dose during the therapeutic cycle, and improvement of the bioavailability of the drug ...
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CarbonAI - Small Molecule Drug Design Services

CarbonAI - Small Molecule Drug Design Services

by:Ainnocence Inc.   based inSacramento, CALIFORNIA (USA)
Simple : CarbonAI searches over 1.9 billion compounds to create synthesizable drug candidates – based only on target sequence. Precise : CarbonAI accurately identifies the most active and safe compound with a multi-objective optimization ...
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Target-to-Lead Services

Target-to-Lead Services

by:CrystalsFirst GmbH   based inMarburg, GERMANY
Crystalsfirst Unlocks Chemical Matter On Scale By Putting Structural Data First. We have developed technologies that overcome current limitations of small molecule drug discovery. The integration of our high-performance structural biology, compound libraries with computational chemistry capabilities identifies novel molecules and druggable ...
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Events Services

Events Services

by:Lightcast Discovery Ltd.   based inCambridge, UNITED KINGDOM
Finding rare events: The Lightcast platform is designed to have a high throughput and will be ideally suited to finding one in 10,000 or one in 100,000 ...
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Small Molecule Drug Development

Small Molecule Drug Development

Manufactured by:Creative Biolabs   based inShirley, NEW YORK (USA)
mall molecule drugs are chemically synthesized active organic compounds with a low molecular weight usually less than 900 daltons which can be made into tablets or capsules that are easily absorbed. As traditional form of medicine, small molecule drugs have always been an important part of drug research and have ...
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Bispecific and Trispecific Antibodies Services

Bispecific and Trispecific Antibodies Services

Manufactured by:Absolute Antibody Ltd   based inRedcar, UNITED KINGDOM
Binding multiple epitopes with a single antibody offers several benefits. For example, one specificity may target individual molecules while another could recruit effector cells or deliver a drug to the target. Other options include dual-target bispecifics which might detect a desired cell type with much higher selectivity than a monospecific antibody. One of ...
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CD Formulation - One-Stop Solution for Small Molecule Drug Formulation

CD Formulation - One-Stop Solution for Small Molecule Drug Formulation

Manufactured by:CD Formulation   based in, NEW YORK (USA)
One-Stop Solution for Small Molecule Drug Formulation: Small molecule drugs are chemically synthesized small molecules of active substances. Small molecule components can be made into tablets or capsules that are easily absorbed by the body. CD Formulation has extensive research experience in ...
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Hit-to-Lead and Lead Optimization Services

Hit-to-Lead and Lead Optimization Services

by:Strateos Inc.   based inMenlo Park, CALIFORNIA (USA)
Hit optimization is a critical step in drug discovery to funnel into lead optimization. Select the most promising hits and leverage H2L, and automated chemical synthesis workflows for faster experimental screening cycles, decreased duration and hands on time, reducing the overall drug discovery timeline leading to promising preclinical candidates. Rapid ...
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adc analysis

adc analysis

Manufactured by:Creative Biolabs   based inShirley, NEW YORK (USA)
The construction of an antibody-drug conjugate (ADC) is the covalent coupling of a monoclonal antibody and a toxic payload drug via a linker molecule. The ultimate goal for an ADC development project is to deploy the resulted ADC into in vivo systems, both in model animals and eventually human patients, to cure cancer and other diseases utilizing ...
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