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Drug Concentration Services
6 services found
Manufactured by:OnLume Inc. based inMadison, WISCONSIN (USA)
OnLume Surgical’s novel approach to fluorescence-guided surgery provides superior imaging with high sensitivity allowing low fluorescent drug concentrations – even under ambient OR light conditions. And, our imaging device is adaptable and applicable to a broad spectrum of targeted fluorescent drugs for applications across the full ...
Manufactured by:Newcells Biotech Limited based inNewcastle Upon Tyne, UNITED KINGDOM
Investigate renal drug transport modalities and drug interactions in vitro. aProximate™ PTCs retain high expression of the relevant transporters involved in drug handling including megalin and cubilin; so are ideal for drug transporter and drug interaction studies of both small and large molecules. Transporters play a major role in the uptake and efflux of drugs across cellular membranes. ...
Manufactured by:Newcells Biotech Limited based inNewcastle Upon Tyne, UNITED KINGDOM
Cross-species comparison of drug handling with near-physiological kidney transporter model. New drug molecules are usually tested in vivo in two preclinical species to gain a more detailed understanding of how they are transported and eliminated through the kidney and also to mitigate risk of renal toxicity in humans. However, these animal models are not always predictive of human responses. To ...
Manufactured by:Cloud-Clone Corp. based inKaty, TEXAS (USA)
Pharmacokinetics mainly study dynamic changes of drug metabolism in body, including drug absorption, distribution and excretion. The research will analyze the drugs and their metabolites by collecting samples in different tissues, organs at different time point. The pharmacokinetic experiments in vivo and in vitro can be designed according to customers’ ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
PROTACs represent a novel strategy for protein degradation that has gained prominence recently. Utilizing bifunctional molecules, PROTACs enable the targeted ubiquitination and subsequent degradation of proteins via the UPS. PROTACs can not only offer potential therapeutic applications for a variety of conditions, including cancer, immune dysregulation, viral infections, and neurodegenerative ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Nanoparticles (NPs) undergo interactions with serum proteins during systemic administration, which may result in the formation of protein corona (PC). Investigating the interplay between the chemical and biological properties of NPs enhances clinical translation efficiency. NPs with PC can be considered to exhibit a distinct biological ...