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Creative Biogene Genomics Services
17 services found
Manufactured by:Creative Biogene-Mitochondrial Research based inNY, NEW YORK (USA)
According to the research needs of global customers on mitochondrial dynamics, Creative Biogene has developed a series of technical service platforms for mitochondrial genome monitoring and analysis. Rely on mature, advanced technology and an experienced professional team to provide customers around the world with the most comprehensive mitochondrial research services to help you ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Microorganisms serve to ferment foods, decompose wastes, treat sewage, produce metabolites, fuel, enzymes and other bioactive compounds. Manipulation of genomic sequences facilitates the identification and characterization of key genetic determinants in the investigation of biological processes. Creative Biogene has the capacity to specifically modify microbial ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Model plant is a species that has been widely studied. With its characteristics like dwarf phenotype, short life cycle, fertility and small genome, model plant plays a crucial role in plant genomics research. Model plant is highly homologous with other complex plants in molecular level. Therefore, genome research of model plant establishes a ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Lentiviruses can deliver significant amounts of genetic information into host cells and integrate it into the cellular genome. Co-transfection of packaging plasmids and transfer vector into a packaging cell line allows efficient production of lentiviral particles that are released into the supernatant of the cells. Viral particles harvested from the cell supernatant can transduce ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Lentiviruses are powerful tools that have been widely used to efficiently transduce both replicating and quiescent cells. The regular lentiviruses are well-known for possessing the ability to stably integrate into their target cell genomes as proviruses. Integrase-deficient lentivirus (IDLV), also known as non-integrating lentivirus (NILV), is a novel technology derived from the ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Lentiviruses can deliver significant amounts of genetic information into host cells and integrate it into the cellular genome. Co-transfection of packaging plasmids and transfer vector into a packaging cell line allows efficient production of lentiviral particles that are released into the supernatant of the cells. Viral particles harvested from the cell supernatant can transduce ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Creative Biogene has developed a series of Cas9 expressing stable cell lines. The Cas9 encoding gene is stably integrated into either random site, or AAVS1 safe harbor site of human genome, or ROSA26 safe harbor site of mouse genome. Apart from HEK293 and HeLa cells, we have achieved Cas9 stable expression in several types of cancer cells which makes it ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Creative Biogene is a leading biotechnology company which has the expertise in providing microbial target genome editing service for customers worldwide. Creative Biogene possesses sophisticated equipment, advanced technologies and highly experienced staffs, which are available to offer you the high-quality, comprehensive service with the most competitive price. ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Genomic engineering in cell lines is a versatile tool for studying gene function, designing diseases models, biopharmaceutical research, drug discovery and many other applications. CRISPR (Clustered Regulatory Interspaced Short Palindromic Repeats)/Cas9 systems is a newly developed yet the most popular method for genome editing. It has been widely used in current ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Creative Biogene CRISPR/Cas9 PlatformCB has established a cost-effective, high-throughput strategy for identifying CRISPR/Cas-induced on/off-target mutations via deep sequencing of PCR amplicons. Based on years of experience in genome editing and off-target effects analysis, we offer one-stop solution to accurately detecting mutations induced by sequence-specific nucleases. Our ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
CRISPR/Cas9 technology has been used as a genome-editing tool for multiple cell lines, such as tumor cell line and embryonic stem cell lines. Primary T cell, as an important class of immune cells system, play an extremely important role in immunity system. It holds great potential for therapeutic applications to engineer genome in primary T cells. However, ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Creative Biogene's sophisticated equipments, advanced technologies and highly experienced staffs are available to provide you the complete siRNA screening service including whole genome-wide siRNA Screening or gene set siRNA screening (ex. apoptosis, GPCR, ion channel, kinase, et al ). Creative Biogene's goal is to provide you with the most affordable and high-quality siRNA ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
CRISPR/Cas9 PlatformCB provides custom libraries for any set of genes of interest, as well as non-coding RNA and regulatory domains, for genome-wide CRISPRa and CRISPRi screening in human, mouse, rat, zebrafish, C. ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
dCas9 can be fused with a gene repressor protein, the KRAB protein, to form a complex CRISPRi (CRISPR interference) that inhibits gene expression. dCas9-KRAB targeting to the promoter region causes steric hindrance that halts transcript elongation by RNA polymerase, resulting in the target gene being repressed. CRISPR-based gene interference provides an efficient and specific ...
Manufactured by:Creative Biogene-Mitochondrial Research based inNY, NEW YORK (USA)
Creative Biogene is committed to mitochondrial research, providing global customers with mitochondrial genomics services, mitochondrial proteomics services, and other custom mitochondrial research services. We have advanced platforms, equipment, a team of experts with rich experience, and standard system processes to offer state-of-the-art mitochondrial custom services to our ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
However, actively and passively integrating (viral) vectors may fail to deliver, or trigger severe side effects by undirected or unintended integration into the genome of the target cell. Thus, the analysis of vector integration sites in target cells is extremely important to address both biological and safety issues. Creative Biogene, as one of the leading biotechnology ...
Manufactured by:Creative Biogene based inShirley, NEW YORK (USA)
Lentivirus is a powerful tool for delivering target genes into almost all types of dividing and non-dividing mammalian cells and may incorporate its genome into that of the host cells. A stable and long-term gene expression can be obtained due to its high transduction efficiency and broad host ...