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Metabolism Drug Services In Usa
15 services found
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Pooled Human Hepatocytes are the chief functional cells of the liver, responsible for the selective uptake, metabolism and excretion of most drugs. Cells for use in plate cultures or suspension assays represent a key tool for predicting properties such as hepatotoxicity, metabolism, and potential drug-drug ...
Manufactured by:CD Formulation based in, NEW YORK (USA)
Solubility and bioavailability issues run through drug metabolism and pharmacokinetic evaluation of candidate compounds, preclinical prescription development, and commercial formulation development. From the toxicological evaluation stage, CD Formulation has a perfect drug metabolism and pharmacokinetic support system, each ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Cell lines are an important research tool, often used in place of primary cells and intact organisms to study biological processes. Cell lines have long been used for a variety of applications such as testing drug metabolism and cytotoxicity, gene function studies, generation of artificial tissues, and synthesis of biological compounds. LK 2 Cell ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Cell lines are an important research tool, often used in place of primary cells and intact organisms to study biological processes. Cell lines have long been used for a variety of applications such as testing drug metabolism and cytotoxicity, gene function studies, generation of artificial tissues, and synthesis of biological compounds. LU99 Cell ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Cell lines are an important research tool, often used in place of primary cells and intact organisms to study biological processes. Cell lines have long been used for a variety of applications such as testing drug metabolism and cytotoxicity, gene function studies, generation of artificial tissues, and synthesis of biological compounds. The C106 cell line was ...
Manufactured by:Charles River based inHollister, CALIFORNIA (USA)
Discovering and characterizing novel drug candidates for preclinical development depends on innovative and reliable science. Our unique combination of integrated, multidisciplinary drug discovery expertise and unparalleled scope of capabilities in targets, platforms, and therapeutic areas allow us to deliver depth and breadth in science with data and insight you can trust to progress your drug ...
by:RTI International based in, NORTH CAROLINA (USA)
RightLeftFor more than 50 years, drug discovery and development has been one of our core research activities. We work with pharmaceutical companies and government agencies to bring new medicines to market, and to ensure the safety and efficacy of those in the marketplace. Our in-depth experience, commitment to excellence, and state-of-the-art facilities make us a valuable ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
KEGG (Kyoto Encyclopedia of Genes and Genomes) database is a database used for systematic analysis of metabolic pathways and functions of gene products in cells. KEGG helps to study genes and its expression information as a whole network. KEGG integrates data from genomes, chemical molecules, and biochemical systems, including metabolic pathways (PATHWAY), ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
Creative Bioarray provides various in vitro ADME/PK services including high-throughput ADME screening, in vitro metabolism, in vitro permeability and transporter assays. ADME is short for "absorption, distribution, metabolism, and excretion". The four properties determine the drug level within a body, the drug exposure to ...
Manufactured by:Cambrex Corporation based inEast Rutherford, NEW JERSEY (USA)
Cambrex has extensive experience in Drug Metabolism and Pharmacokinetic (DMPK), Bioanalytical and Biopharmaceutical Analyses. The Biopharmaceutical Analyses scope supports GMP method development, validation, and routine analysis including but not limited to host cell proteins, host cell DNAs, endotoxins, enzyme kinetics, and even bacteriophage titering assays. ...
by:Inotiv based inWest Lafayette, INDIANA (USA)
Inotiv offers a broad scope of expertise for drug metabolism and pharmacokinetics (DMPK) studies at all stages of R&D, from lead optimization through NDA. Benefit from our long and impeccable regulatory history, world-class team of scientists, and 40+ year track record of providing leading pharma and biotech companies with attentive, decisive analytical ...
Manufactured by:Altis Biosystems based inDurham, NORTH CAROLINA (USA)
Accurate biological screening based on real human intestinal tissue, with a standardized workflow for reliable and reproducible data, RepliGut represents ?the next generation for in vitro testing with faster actionable data. ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Urine contains a vast array of chemicals, including microbial metabolites and mammalian metabolic products. Drugs, pollutants, and industrial chemicals may also be present in urine. Since urine lacks homeostatic regulation, it can reflect metabolic disturbances, providing insights into systemic changes in response to physiological challenges or ...
Manufactured by:LAMPIRE Biological Laboratories, Inc. based inPipersville, PENNSYLVANIA (USA)
LAMPIRE's high-tech vivarium and staff are available for your lab animal projects. The expanded capacity and enhanced facilities can accommodate drug metabolism and pharmacokinetic (DMPK) studies, teratogenicity studies, small- and large-scale hybridoma projects, and much more. One of the biggest challenges in preclinical research is procuring high quality animal ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Many drugs target proteins that function as receptors for small-molecule ligands. These ligands bind to and alter the structures of their protein targets, thus modulating their biological activities. Key protein targets in the fields of biology and pharmaceutical research include the nuclear receptors (NRs) that belong to the superfamily of ligand-dependent transcription factors, the ...