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Targeting Disease Services
18 services found
Manufactured by:MODAG GmbH based inWendelsheim, GERMANY
Certain proteins including α-synuclein can form disease-specific fibrillar amyloid aggregates. The misfolding/ aggregation pathway resulting in amyloid fibrils involves characteristic oligomer species which have been shown to be the most relevant toxic protein species. These pathological oligomers exhibit structural epitopes that are not found in physiologically folded ...
Manufactured by:ImmunoPrecise Antibodies Ltd. based inVictoria, BRITISH COLUMBIA (CANADA)
We support our business partners in the quest to discover and develop novel antibodies against a broad range of classes of disease targets in “one-stop”, with:? An unrivaled suite of services. Target design and antigen modeling. A broad range of immunization technologies in a multitude of species and strains. Best-in-class hybridoma, ...
Manufactured by:Deep Genomics based inToronto, ONTARIO (CANADA)
AI Drives Unprecedented Number of Valuable Medicines by Combining Prediction and Scale. Our proprietary AI Workbench is designed for data-driven prediction, positive feedback loops, and exponential growth. It enables us to identify leads for over 50% of the novel targets we select, and to do so quickly. This is a game changer. In 2018, our proprietary AI Workbench unlocked our first targets in ...
by:Genmab A/S based inCopenhagen V, DENMARK
Our research and innovation teams consist of a strong antibody discovery engine connecting our antibody platform technologies with our target and disease biology knowledge. This synergy is the lifeblood of our R&D organization, where our creations enter clinical ...
by:Amgen Inc. based inThousand Oaks, CALIFORNIA (USA)
Understanding the fundamental biological mechanisms of disease is a defining feature of Amgen's discovery research efforts—and a major contributor to the development of Amgen's deep and broad pipeline of potential new medicines. Amgen's "biology first" approach permits its scientists to first explore the complex molecular pathways of disease before ...
Manufactured by:Creative Bioarray based inShirley, NEW YORK (USA)
They play an extensive role in signal transduction and regulation of the complex cellular processes necessary to maintain life. Overexpression and/or dysregulation of protein kinases lead to a variety of diseases, thus providing numerous targets for drug development. Currently, approximately 24% of all research spending on drug discovery and development is ...
Manufactured by:Creative Biogene-Mitochondrial Research based inNY, NEW YORK (USA)
To further meet the needs of multi-group joint analysis, through the integrated analysis of multi-group data, Creative Biogene provides a systematic and overall solution for global researchers, such as mitochondrial regulation mechanism, disease target screening, biomarker discovery, and so on. We provide new ideas for researchers studying mitochondrial molecular ...
Manufactured by:Synbio Technologies LLC based in, NEW JERSEY (USA)
The immune system is a very robust “antibody factory” that consistently produces antibodies to fight infections and diseases by recognizing and targeting infected cells or pathogens (antigens). The emergence of single B cell antibody technology has enabled a new strategy for discovery of naturally occurring antibody drugs. The single B cell antibody ...
Manufactured by:Kiadis Pharma NV based inAmsterdam, NETHERLANDS
Our efforts in haematology are currently focussed on non-malignant blood disorders including forms of anaemia. Our approach is to identify functional and developable lead molecules and quickly proceed to verified animal disease models to study the direct impact of our drug candidates with clinically relevant read outs. We build our know-how by working on common pathways that are ...
by:Genmab A/S based inCopenhagen V, DENMARK
Increasingly, data are transforming our understanding of diseases. This is especially true in cancer. We have invested in robust data science capabilities to enable rapid data-driven decision making as we advance our products through all stages of development. Integration of disparate data sets from clinical and pre-clinical studies is a major guiding principle that is allowing ...
Manufactured by:Inovotion Sas based inLa Tronche, FRANCE
Target validation is an essential and critical phase of the drug discovery process. This is a crucial step before starting to develop a treatment based on a targeted protein that has been identified to play a role in the disease. The target protein’s role must be clearly identified before starting to develop a drug ...
Manufactured by:CENTOGENE N.V. based inRostock, GERMANY
We provide a broad range of services to successfully operate clinical trials. We leverage our proprietary Bio/Databank, multiomic platform, extensive physician network and our experts to ensure efficient and effective solutions to drive progress in the rare disease ...
by:Molecular Health GmbH based inHeidelberg, GERMANY
Act beyond human and experimental limitations. Knowledge to advance game-changing therapies from idea to market. The world's biomedical knowledge at your fingertips. Reliable predictions to anticipate risks. Interlinked data to find new targets and design novel drugs. Real-world evidence to evaluate success. These capabilities eliminate the uncertainties that limit drug development but are ...
Manufactured by:CENTOGENE N.V. based inRostock, GERMANY
We work with partners to develop new disease models and new biomarkers of disease. We can also use our disease models to identify new drug targets and screen chemical compounds to identify potential new drug candidates. CENTOGENE provides companies with tools to accelerate drug discovery. From population screening studies that ...
by:Creative Proteomics based inNew York, NEW YORK (USA)
KEGG, abbreviation of Kyoto Encyclopedia of Genes and Genomes, is a collection of databases, which is used for bioinformatics research, including data mining in genomics, proteomics, metabolomics and other omics studies, modeling and simulation in systems biology, and translational research in drug R & ...
by:Oncimmune Holdings PLC based inNottingham, UNITED KINGDOM
Autoimmune disease is caused by the breaking of self-tolerance. Oncimmune’s understanding of the immune system as a mediator of disease powers the ImmunoINSIGHTS service for autoimmune ...
by:ForeSee Medical, Inc. based inSan Diego, CALIFORNIA (USA)
While healthcare data companies develop additional complex analytics technologies, personalized healthcare organizations are moving from ordinary analytics towards an area of predictive health insights to better understand current challenges and potential outcomes. Rather than just being presented information from previous events to an end user, healthcare predictive analytics approximate the ...
by:MtoZ Biolabs based in, MASSACHUSETTS (USA)
Antibody therapies leverage human immune system antibodies to treat diseases by targeting specific proteins on pathogens or abnormal cells with exceptional precision. The development of antibody therapies has evolved from early polyclonal sera to monoclonal antibodies, and now to genetically engineered antibodies, focusing on enhancing drug safety, effectiveness, ...