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Physiological Relevance Product Applications In North America
4 applications found
These tools can interrogate large numbers of mutations in cell surface receptors and many globular proteins, offering a unique path forward for protein optimization based on high quality, physiologically-relevant data in eukaryotic or – specifically – human ...
ByCyrus Biotechnology Inc. based in Seattle, WASHINGTON (USA)
Using 3D bioprinters can create physiologically-relevant cellular disease models to test therapeutic hypothesis by accurately and reproducibly controlling the deposition of different cell types and support materials, providing a viable technology solution for drug discovery projects. ...
ByRegenhu based in Villaz-St-Pierre, SWITZERLAND
Facilitate the construction of human skin equivalents for wound healing research, cosmetic product development or drug delivery ...
ByRegenhu based in Villaz-St-Pierre, SWITZERLAND
Increase clinical translation with Organ-Chips for ADME-Tox assessments. Accurate ADME-Tox profiling of preclinical drug candidates remains a challenge. Preclinical ADME-Tox (Absorption, Distribution, Metabolism, Excretion, and Toxicity) studies are pivotal to predicting human response. However, approximately 30% of drugs fail during human clinical trials due to adverse reactions despite promising preclinical study results, and another 60% fail due to lack of efficacy. As companies broaden the modality toolbox ...
ByEmulate based in Boston, MASSACHUSETTS (USA)