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Physiological Relevance Equipment Supplied In North America
24 equipment items found
by:BICO - The Bio Convergence Company based inBoston, MASSACHUSETTS (USA)
Create multimaterial constructs with a mix of crosslinking modalities thanks to six printheads. 6 printheads enabling more complex structures and physiologically relevant ...
Manufactured by:CELLINK based inBoston, MASSACHUSETTS (USA)
Create multimaterial constructs with a mix of crosslinking modalities thanks to six printheads. 6 printheads enabling more complex structures and physiologically relevant ...
by:Thermo Fisher Scientific, LIMS & Laboratory Software based inPhiladelphia, PENNSYLVANIA (USA)
Create physiologically relevant cell culture models. Gibco Human Plasma-like Medium (HPLM) is a new formulation designed to resemble the natural cellular environment found in the body, mimicking the metabolic profile of human plasma. The widely used classic synthetic cell culture media, including MEM, DMEM, RPMI 1640, and DMEM/F-12 contain glucose, amino acids, ...
Manufactured by:InSphero AG based inSchlieren, SWITZERLAND
The 3D InSight™ Steatosis Model is an advanced human disease model that enables you to screen compounds and investigate disease pathophysiology using a physiologically relevant human liver microtissue that recapitulates the first stage of non-alcoholic fatty liver disease: accumulation of lipids in liver hepatocytes. Available as an assay-ready model ...
Manufactured by:Mimetas B.V. based inLeiden, NETHERLANDS
The product is based on the OrganoPlate® 3-lane 40 with 3 adjacent channels per chip, including one perfused HUVEC tubule. Do you want to perform experiments in human-relevant, complex 3D tissue models but don’t have the time or experience to build your own? Look no further, with the OrganoReady Blood Vessel HUVEC you can now take your vascular research to the next ...
Manufactured by:Mimetas B.V. based inLeiden, NETHERLANDS
OrganoReady® Caco-2 comprises 38 ready-to-use Caco-2 tubules for drug exposure, transport, and permeability studies. Do you want to perform experiments in human-relevant, complex 3D tissue models but don’t have the time or experience to build your own? Look no further, with the OrganoReady Colon Caco-2 you can now easily take your intestinal research to the next level. ...
Manufactured by:Pinnacle Technology based inLawrence, KANSAS (USA)
Pinnacle offers a GLUTAMATE BIOSENSOR that is capable of providing real-time changes in glutamate concentration in the brains of rodents. The glutamate biosensor has outstanding performance characteristics and rejects all common electroactive interferents, including ascorbate. It has a linear range of at least 50 uM. We have successfully demonstrated that the glutamate biosensor works in vivo ...
Manufactured by:Pinnacle Technology based inLawrence, KANSAS (USA)
Pinnacle offers a GLUCOSE BIOSENSOR that is capable of providing real-time changes in glucose concentration in the brains of rodents. The glucose biosensor has outstanding performance characteristics and rejects all common electroactive interferents, including ascorbate. It has a linear range of at least 4 mM. We have successfully demonstrated that the glucose biosensor works in vivo and can ...
Manufactured by:Pinnacle Technology based inLawrence, KANSAS (USA)
Pinnacle offers a LACTATE BIOSENSOR that is capable of providing real-time changes in lactate concentration in the brains of rodents. The lactate biosensor has outstanding performance characteristics and rejects all common electroactive interferents, including ascorbate. It has a linear range of at least 2 mM. We have successfully demonstrated that the lactate biosensor works in vivo and can ...
by:BICO - The Bio Convergence Company based inBoston, MASSACHUSETTS (USA)
Automated sorting and isolation of single spheroids and organoids. A game-changer in drug screening and other applications where standard 3D models will gradually replace traditional animal models. spheroONE is an innovative single large-particle sorter and dispenser which revolutionizes 3D cellular models handling. Using precision dispensing technology together with advanced image-based sorting ...
Manufactured by:Platypus Technologies, LLC based inMadison, WISCONSIN (USA)
In the Oris 3D Cell Invasion Assay, stoppers are used to create a central collagen-containing Detection Zone for cell invasion experiments. Cells are suspended in a thick layer of collagen surrounding a circular collagen Detection Zone. After incubation, invading cells move into the detection zone, where they can be unambiguously quantified using a microscope or a ...
Manufactured by:ScienCell Research Laboratories based inCarlsbad, CALIFORNIA (USA)
They are also capable of trans-differentiating into myofibroblasts, suggesting a role in aberrant accumulation of matrix and fibrotic disorders. CMEC cultures provide an invaluable tool for understanding CMEC physiological and pathophysiological relevance in cardiac function and disease. ...
Manufactured by:Mimetas B.V. based inLeiden, NETHERLANDS
OrganoReady® Angiogenesis HUVEC comprises 64 HUVEC tubules ready-to-sprout. The product is based on the OrganoPlate® 3-lane 64 with 3 adjacent channels per chip, including one perfused HUVEC tubule. Do you want to perform experiments in human-relevant, complex 3D tissue models but don’t have the time or experience to build your own? Look no further, with the OrganoReady Angiogenesis ...
Manufactured by:Emulate based inBoston, MASSACHUSETTS (USA)
Evaluate drug candidate toxicity at clinically relevant concentrations in a co-culture human kidney model. Predicting drug-induced kidney toxicity and drug-drug interactions continues to be a challenge due to a reliance on immortalized cell line culture or animal models that do not translate to human response. The co-culture Emulate Kidney-Chip combines primary human cells in a dynamic ...
Manufactured by:Organovo Holdings Inc. based inSan Diego, CALIFORNIA (USA)
While the bioprinting process is cell-agnostic, our bioprinted tissues utilize primary human cells where possible in order to produce the in vivo-like physiology most relevant for drug testing. We utilize multiple independent sources for our input cells to allow patient selection and high levels of ...
Manufactured by:Emulate based inBoston, MASSACHUSETTS (USA)
Study drug absorption and drug-drug interactions in a primary organoid-based model of the human small ...
Manufactured by:Shared Imaging based inDowners Grove, ILLINOIS (USA)
The PET component uses positron-emitting radionuclides to label biologically significant molecules, like sugars. The decay of these tracers is detected by the PET scanner, which creates physiologic maps of relevant functions or processes. Clinically, FDG, a glucose analog, is commonly used to image glucose metabolic rates in oncologic studies, exploiting the ...
by:Empatica Inc. based inBoston, MASSACHUSETTS (USA)
The E4 is a medical-grade wearable device that offers real-time physiological data acquisition, enabling researchers to conduct in-depth analysis and ...
Manufactured by:Emulate based inBoston, MASSACHUSETTS (USA)
Investigate mechanisms of toxicity for preclinical drug candidates to help decrease clinical trial safety failures. Drug-induced liver injury (DILI) is a primary concern during drug development that remains poorly understood due to species differences in liver toxicity and the limited predictivity of conventional in vitro models. The quad-culture Emulate Liver-Chip combines four human cell types ...
Manufactured by:InSphero AG based inSchlieren, SWITZERLAND
Test efficacy of anti-NASH drugs in an advanced 3D human liver disease model. The InSphero 3D InSight™ Human Liver NASH Model consists of an advanced microtissue co-culture of healthy primary human liver cells combined with specially formulated media and cocktails that induce the progression of NAFLD and NASH from steatosis to liver inflammation and fibrosis. Ideal for investigating ...