Show results for
Refine by
Assay Product Applications In Usa North Carolina
4 applications found
However, as applications increasingly rely on ultra low variant allele frequency detection, NGS-based assays are beset with significantly more noise below 0.5% VAF that increases the rate of false positives. Laboratories looking to implement ctDNA assays need better quality controls that can ensure accurate detection and reporting by variant calling algorithms.Standardizing within patient measurements and across sites and platforms are equally critical to ensuring accurate ...
ByAccuGenomics, Inc. based in Wilmington, NORTH CAROLINA (USA)
A challenge to widespread adoption of RNASeq transcript abundance measurement for clinical studies and diagnostics is yield biases between targets affecting accuracy and reproducibility of the assay. Implementing a unique molecular index (UMI) approach can reduce bias, but at a cost of >8 fold increase in read ...
ByAccuGenomics, Inc. based in Wilmington, NORTH CAROLINA (USA)
Tracking SARS-CoV-2 viral strain evolution is critical for monitoring new regional outbreaks, contact tracing, infection control and verifying the performance of front-line RT-PCR diagnostic assays. Being able to report accurate sequence variations confidently, is critically ...
ByAccuGenomics, Inc. based in Wilmington, NORTH CAROLINA (USA)
The manufacture of biopharmaceutical agents such as therapeutic monoclonal antibodies, vaccines and cell-based therapies like CAR-T cells require the highest quality control against the contamination of adventitious agents. These pathogens can enter the manufacturing process at multiple stages and impact yield and safety. Current methods for detection of adventitious agents are expensive, lack sensitivity and have long turn around times to results. Moreover, many of the current adventitious agent testing methods ...
ByAccuGenomics, Inc. based in Wilmington, NORTH CAROLINA (USA)