Leukemia Cell Articles & Analysis
7 articles found
Among the various forms of immunotherapy, CAR T-cell therapy (Chimeric Antigen Receptor T-cell therapy) has shown promise, particularly in treating acute lymphoblastic leukemia (ALL), especially in children and young adults. This therapy involves genetically modifying a patient’s T-cells to express a receptor specific to ...
Diseases Associated with CD19 CD19 is implicated in various significant diseases, including: 1) B-Cell Lymphoma: B-cell lymphoma, a type of leukemia and lymphoma arising from lymphoid tissue, shows overexpression of CD19 on the surface of B cells in certain patients. ...
These results indicated that tetrahydrocurcumin could protect and prevent cell membrane damage caused by lipid peroxidation. The results of the present study also suggest that the antioxidant effect of tetrahydrocurcumin may be related to the increase of oxidative stress. 3.Anti-fatty Liver Effect Pan Xuefeng et al. studied the anti-fatty liver effect of tetrahydrocurcumin on ...
Abstract Natural killer (NK) cells are emerging as a new tool for cell therapy of cancer. However, some cancer subtypes are relatively resistant to NK cell cytotoxicity. Expression of anti-CD19 chimeric signaling receptors can enhance NK-cell reactivity against CD19+ leukemia and lymphoma ...
Lymphocyte-activation gene 3 (LAG-3), also known as CD233, is a type I transmembrane protein expressed mainly in activated T cells, NK cells, B cells, and plasma cell-like DCs. Oncology and autoimmune diseases (rheumatoid arthritis, multiple sclerosis) are currently among the clinical pipeline indications for LAG-3 which acts as ...
The anti-apoptotic myeloid cell leukemia 1 (MCL1) protein belongs to the BCL2 family that supports survival and is frequently amplified or upregulated in human cancers. ...
A common feature of tumor cells is the aberrant expression of ion channels on their plasma membrane. The molecular mechanisms regulating ion channel expression in cancer cells are still poorly known. K+ channels that belong to the human ether-a-go-go-related gene 1 (herg1) family are frequently misexpressed in cancer cells compared to their ...