Leukemia Cell Articles & Analysis
3 news found
Senti Bio’s oncology pipeline is primarily focused on three preclinical-stage programs: SENTI-202, a Logic Gated (OR+NOT) off-the-shelf CAR-NK cell therapy designed to target and eliminate acute myeloid leukemia (AML) cells while sparing the healthy bone marrow; SENTI-301, a regulatable Multi-Armed off-the-shelf CAR-NK cell ...
Lentiviruses are widely used as a tool to deliver genes of interest to cells. In this case, the lentivirus transduces (or inserts) a group of genes to a patient’s T cells (immune cells), which turn the T cells into cancer-killing CAR-T cells targeting LGR5, a cancer stem cell marker found ...
The successes observed with hematologic malignancies have revolutionized anticancer therapy, providing a potentially curative option for patients with pre-B cell acute lymphoblastic leukemia (ALL) or B cell lymphomas. There is a substantial effort being made towards expanding the impact of this line of therapy to other tumor types, mainly solid ...