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Liver Transplant Articles & Analysis

8 articles found

Cell Transplantation Promising for Treatment of Biliary Diseases   

Cell Transplantation Promising for Treatment of Biliary Diseases  

Biliary disease is a term used to describe diseases that affect the biliary system, which can result in inflammation, fibrosis, bile duct destruction, and eventually liver failure. It also frequently leads to secondary infections and chronic irritation, such as bile duct stones, which can lead to malignant tumors. There is currently no cure for biliary tract diseases other than liver ...

ByCreative Biolabs


In Silico Development of Combinatorial Therapeutic Approaches Targeting Key Signaling Pathways in Metabolic Syndrome

In Silico Development of Combinatorial Therapeutic Approaches Targeting Key Signaling Pathways in Metabolic Syndrome

Purpose Dysregulations of key signaling pathways in metabolic syndrome are multifactorial, eventually leading to cardiovascular events. Hyperglycemia in conjunction with dyslipidemia induces insulin resistance and provokes release of proinflammatory cytokines resulting in chronic inflammation, accelerated lipid peroxidation with further development of atherosclerotic alterations and diabetes. We ...

ByVeriSIM Life


Improved Sepsis Detection & Compliance: 6 Areas your Next Solution should Address

Improved Sepsis Detection & Compliance: 6 Areas your Next Solution should Address

Sepsis accounts for over 20% of deaths worldwide (WHO) and 85% of cases occur in low-resource settings.But this isn’t a problem mostly owned by third-world countries with inadequate equipment and detection technology. In the U.S., less than 50% of patients are correctly treated for sepsis, mostly due to clinicians missing the timeline for treatment. The problem is so widespread that ...

ByAmbient Clinical Analytics


Extra Innings: Kevin Kronmiller’s Story - Case Study

Extra Innings: Kevin Kronmiller’s Story - Case Study

The Problem: When Kevin Kronmiller was 22, he found out he had 5 years to live if he didn't receive a liver transplant. Beating the odds, Kevin made it to 50 before needing a liver transplant. After his surgery, Kevin went into Septic Shock. He found out later from his physicians that he had a 30% chance of survival and even if he did survive, doctors were very concerned about long-term ...

ByAmbient Clinical Analytics


Modeling NAFLD using 3D bioprinted human liver tissue

Modeling NAFLD using 3D bioprinted human liver tissue

Publication Summary: Nonalcoholic fatty liver disease (NAFLD) is a chronic condition that originates as lipid accumulation within hepatocytes (steatosis) and progresses into nonalcoholic steatohepatitis (NASH), characterized by lipid accumulation, inflammation, oxidative stress, and fibrosis. NAFLD is now recognized as the most common cause of chronic liver disease in the western world, with an ...

ByOrganovo Holdings Inc.


Expanding Our Commitment to Rare Disease Therapeutics

Expanding Our Commitment to Rare Disease Therapeutics

Each year, the last day of February serves as a reminder to pause and reflect on the challenges and unique needs of patients and families living with rare diseases. It is an opportunity for all members of the patient, medical, and scientific communities to shine a light on the urgent need to improve the care and support for those impacted by such conditions. At Moderna, we are working to ...

ByModerna, Inc.


Modeling NAFLD using 3D bioprinted human liver tissue

Modeling NAFLD using 3D bioprinted human liver tissue

Publication Summary: Nonalcoholic fatty liver disease (NAFLD) is a chronic condition that originates as lipid accumulation within hepatocytes (steatosis) and progresses into nonalcoholic steatohepatitis (NASH), characterized by lipid accumulation, inflammation, oxidative stress, and fibrosis. NAFLD is now recognized as the most common cause of chronic liver disease, with a prevalence of 25% ...

ByOrganovo Holdings Inc.


Bioartificial liver: review of science requirements and technology

Bioartificial liver: review of science requirements and technology

Social development in health services is concerned as a global issue. More than nine million people die due to internal organ failure and one percent of this number is due to liver disease. In 1990, more than 27,000 deaths in the USA were caused by liver failure. From the numerous reviews on liver failure and associated support therapies, there is increasing interest in this field throughout the ...

ByInderscience Publishers

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