Peripheral Neuropathic Articles & Analysis
17 articles found
Introduction The human body is a complex network of genes and proteins, each playing a crucial role in maintaining our health. One such gene, DNM1L, has garnered significant attention in recent years due to its vital functions and its association with various diseases. In this blog post, we will delve into the world of DNM1L, exploring its function, the diseases it is linked to, and the ...
Carfilzomib, a proteasome inhibitor, is indicated for the treatment of patients with multiple myeloma. Multiple myeloma (multiple myeloma, MM) is a malignant tumor originating from the B cell lineage, characterized by the clonal proliferation of malignant plasma cells in the bone marrow microenvironment, causing fractures and bone marrow failure, and is the second most common blood system ...
Healing rate: 25.3 mm2/day. Healing time: 33 days. Wound size: 38 × 22 × 8 mm. Age of wound when treatment started: > 1 year. Subject: 52/male. Insulin dependent diabetic, peripheral neuropathy, hypertension, renal failure on hemodialysis; history of chronic foot ...
Healing rate: 14.3 mm2/day. Healing time: 103 days. Wound size: 49 × 30 × 3 mm. Age of wound when treatment started: ~ 3 months. Subject: 62/male. Non-insulin dependent diabetes, venous insufficiency, peripheral neuropathy, HTN, CHF, COPD, ...
Healing rate: 5.4 mm2/day. Healing time: 93 days. Wound size: 25 × 20 × 3 mm w/undermining. Age of wound when treatment started: 4 months. Subject: 68/female. Diabetes, peripheral neuropathy, and venous insufficiency. Necrotic tissue was treated with moistened MIRRAGEN™ advanced wound matrix for 2 days to soften and loosen necrotic tissue for easy ...
With this protocol it is possible to assess the voluntary motor function, being appropriate for patients with central nervous system pathologies and peripheral neuropathic disorders, older adults with mobility impairments, and athletes interested in rapid movement reactions and direction changes. ...
INTRODUCTION After a peripheral nerve injury, fast conducting large myelinated afferent A-bcta fiber transmission diminishes over time. ...
Abstract Background. Peripheral nerve injury can result in the formation of neuroma/nerve entrapment, a persistent peripheral neuropathic pain state which is often refractory to invasive interventions or medications. Therefore, there is a need in the field of pain management to develop innovative noninvasive therapy in treating post-traumatic ...
The following are the 7 most common reasons why your hands might be going numb. There could be a rarer reason (also listed below) for this problem, but you should look into the most common ones first. About Your Numbness In order to better understand what's causing your numb hands it's necessary to consider these 3 questions: Do you have numb hands all of the time or just ...
In medicine, taking a holistic approach means treating the whole person - body, mind, spirit, and emotions - to achieve one’s optimal health and wellness. For example, if a patient comes in with a sharp, jabbing pain in his hand - a symptom of peripheral neuropathy - a holistic treatment plan may not only include pain relief medicine but also address underlying causes of pain. A holistic ...
Christine Salcher, DPM Sherman, Texas and Amyee McAlister, Healthline Patient: 50-year-old Caucasian female with a pressure ulcer that has progressively gotten larger, deeper, more malodorous, fibrotic, and necrotic Comorbidities: Diabetes, diabetic retinopathy & peripheral neuropathy Age of Wound: 90 days Days on Service: 55 days Outcome: Goals met. Wound healed. High patient ...
Novel cytotoxic drugs New cytotoxic drugs have been developed to target cancer cells with low antigen expression or resistance to auristatins or maytansinoids. For this purpose, PBD dimers have been developed, which have a molecular structure containing two alkylated imine functional groups capable of forming covalent bonds with DNA.PBD dimers are about 50-100 times more potent than conventional ...
It's abnormal, but not uncommon. Having numb fingers while sleeping affects nearly everybody at least some time in their life. But if it happens night after night for a long time, it's something you should address. Numbness, especially at the fingertips, could be a minor problem or it could signal there's a more serious condition underlying the problem. Here are the possibilities. ...
What is it? Posturography is a non-evasive technique that quantifies an individual’s balance behavior in upright stance. As mentioned in previous articles (What is Balance?), balance is achieved and maintained by a complex set of sensorimotor control systems, which includes the visual, somatosensory and vestibular systems. It is through their integration in real time by the central ...
Doylestown-based Neuropathix is running safety tests required to start clinical trials in humans. The compound may help with neuropathy, a severe type of chronic pain associated with cancer treatment. The next generation of cannabis-inspired medicine might be grown in test tubes instead of greenhouses. Researchers at Temple University have partnered with Doylestown-based pharmaceutical company ...
When tested on mice, their compound, KLS-13019, demonstrated both prevention and reversal of chemotherapy-induced peripheral neuropathy (CIPN), a common side effect of certain cancer treatments that damage peripheral nerves, which carry sensory information to the arms, legs, and brain. ...
Kannalife is developing proprietary CBD and CBD-like molecules for neurodegenerative disorders, including chemotherapy-induced peripheral neuropathy (CIPN). This is a chronic nerve pain caused by the toxic aspects of chemotherapy drugs. ...