Peripheral Neuropathy Articles & Analysis
17 articles found
One such disease is Charcot-Marie-Tooth disease type 2A (CMT2A), a hereditary peripheral neuropathy characterized by progressive muscle weakness and sensory loss. CMT2A is caused by mutations in the DNM1L gene, leading to impaired mitochondrial fission and subsequent dysfunction of peripheral nerves. Another disease associated with DNM1L is ...
(2) Safety and Tolerability Compared with bortezomib, carfilzomib had less peripheral neuropathy. In RRMM patients, the rate of grade 3 peripheral neuropathy was 1.3%, but no patients had grade 4 events, and only 1% of patients required dose adjustment or Withdrawal. ...
Subject: 52/male. Insulin dependent diabetic, peripheral neuropathy, hypertension, renal failure on hemodialysis; history of chronic foot ...
Non-insulin dependent diabetes, venous insufficiency, peripheral neuropathy, HTN, CHF, COPD, ...
Subject: 68/female. Diabetes, peripheral neuropathy, and venous insufficiency. Necrotic tissue was treated with moistened MIRRAGEN™ advanced wound matrix for 2 days to soften and loosen necrotic tissue for easy ...
The Limits of Stability (LOS) is perhaps the most used protocol in the literature for balance assessment in a dynamic task. It quantifies the ability to intentionally displace the center of gravity to the patient’s stability limits without losing balance. This protocol provides information regarding voluntary motor control, which also helps screening fall risk in elderly people [1]. How ...
INTRODUCTION After a peripheral nerve injury, fast conducting large myelinated afferent A-bcta fiber transmission diminishes over time. On the other hand, firing of smaller pain transmitting fibers such as A-dclta and C-fibcrs is enhanced. This aberrant afferent neuronal behavior is thought to be one of the main neuronal mechanisms leading to development of chronic posttraumatic peripheral ...
Abstract Background. Peripheral nerve injury can result in the formation of neuroma/nerve entrapment, a persistent peripheral neuropathic pain state which is often refractory to invasive interventions or medications. Therefore, there is a need in the field of pain management to develop innovative noninvasive therapy in treating post-traumatic peripheral neuropathic pain states. A new ...
The following are the 7 most common reasons why your hands might be going numb. There could be a rarer reason (also listed below) for this problem, but you should look into the most common ones first. About Your Numbness In order to better understand what's causing your numb hands it's necessary to consider these 3 questions: Do you have numb hands all of the time or just ...
For example, if a patient comes in with a sharp, jabbing pain in his hand - a symptom of peripheral neuropathy - a holistic treatment plan may not only include pain relief medicine but also address underlying causes of pain. ...
Christine Salcher, DPM Sherman, Texas and Amyee McAlister, Healthline Patient: 50-year-old Caucasian female with a pressure ulcer that has progressively gotten larger, deeper, more malodorous, fibrotic, and necrotic Comorbidities: Diabetes, diabetic retinopathy & peripheral neuropathy Age of Wound: 90 days Days on Service: 55 days Outcome: Goals met. ...
However, Adcetris, when used alone, caused potentially severe peripheral neuropathy, neutropenia, and thrombocytopenia, all of which are typical side effects of antiplatelet drugs. ...
These reasons are given in order from the most to least common: Sleeping in a bad position Carpal tunnel syndrome Cubital tunnel syndrome Peripheral neuropathy (diabetes and alcohol abuse) Cervical Spondylosis Raynaud's disease Vascular diseases Stroke Multiple sclerosis Medication Side Effects (Chemotherapy) Vitamin B12 Deficiency Numb finger ...
Reid et al. [6] also used posturography to assess the incidence of large-fiber peripheral neuropathy by comparing the results with conventional electromyography (EMG) results. ...
Doylestown-based Neuropathix is running safety tests required to start clinical trials in humans. The compound may help with neuropathy, a severe type of chronic pain associated with cancer treatment. ...
When tested on mice, their compound, KLS-13019, demonstrated both prevention and reversal of chemotherapy-induced peripheral neuropathy (CIPN), a common side effect of certain cancer treatments that damage peripheral nerves, which carry sensory information to the arms, legs, and brain. ...
Kannalife is developing proprietary CBD and CBD-like molecules for neurodegenerative disorders, including chemotherapy-induced peripheral neuropathy (CIPN). This is a chronic nerve pain caused by the toxic aspects of chemotherapy drugs. ...