Phenotypic Screening Articles & Analysis
4 articles found
The cells can be used as model systems in phenotypic and drug screening, high content analysis, target identification, drug development, toxicology testing, gene editing studies, reporter assays. ...
Turning that vision into reality wasn’t easy; we essentially created a phenotypic screen, and I started coding up machine learning classifiers. ...
To discover novel druggable targets for cancers carrying co-mutations in Ras and p53, we performed arrayed, kinome focused siRNA and oncology drug phenotypic screening utilizing a set of syngeneic Ras mutant squamous cell carcinoma (SCC) cell lines that also carried co-mutations in selected p53 pathway genes. These cell lines were derived from SCCs from ...
You don’t have to be a scientist to see the difference. That led us to do a phenotypic screen, collecting images of healthy and diseased cells to search for potential interventions that may make a diseased cell look healthier. ...