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Phenotypic Screening Articles & Analysis

4 news found

Ace Therapeutics Releases BBBporter™ Technology Platform to Overcome the Challenges of Brain Drug Delivery

Ace Therapeutics Releases BBBporter™ Technology Platform to Overcome the Challenges of Brain Drug Delivery

A multi-modal modular preclinical contract research service based on the BBBporter™ platform l BBB RMT Target Identification and Screening Services: Integrating molecular profiling or “omics” analyses with phenotypic screening approaches, Ace Therapeutics helps brain researchers identify RMT receptors and ...

ByAce Therapeutics


Sosei Heptares and Kallyope Enter Collaboration to Identify and Validate Novel Gastrointestinal GPCR Targets for Drug Discovery

Sosei Heptares and Kallyope Enter Collaboration to Identify and Validate Novel Gastrointestinal GPCR Targets for Drug Discovery

The agreement will leverage Sosei Heptares’ GPCR Diversified Compound Library and GPCR expertise with the innovative Kallyope gut-brain axis platform, which combines single-cell sequencing, circuit mapping, computational biology and enteroid phenotypic screening. Together, the companies will prioritize and validate GPCR drug targets that represent new ...

ByKallyope Inc.


Creative Biostructure Supplies MagHelix™ Zebrafish Screening Platform for Drug Discovery

Creative Biostructure Supplies MagHelix™ Zebrafish Screening Platform for Drug Discovery

This newly established MagHelix™ Zebrafish Screening Platform is an excellent choice for building disease models and screening drugs. ...

ByCreative Biostructure


AACR Presentation #1731 : EXS21546, a non-CNS penetrant A2AR-selective antagonist for anti-cancer immunotherapy

AACR Presentation #1731 : EXS21546, a non-CNS penetrant A2AR-selective antagonist for anti-cancer immunotherapy

Interrogation of primary cancer cells from pancreatic and lung cancer patients treated with EXS21546 ex vivo by phenotypic image-based screening, demonstrated that EXS21546 reduces the relative fraction of viable cancer cells while inducing an expansion of the viable CD8+ T cell fraction in the presence of high concentrations of an adenosine analogue. ...

ByExscientia

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