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Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Contract Manufacturing Organization Alfa Chemistry is the one of the leading companies for ADC drug development in the world that provides technically challenging service from development to commercial production including both payload and ADC. Alfa CDMO is equipped with state-of-the-art fill/finish equipment with aseptic filling and lyophilization with automated operation to ensure manufacturing ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Edaravone, a member of the substituted 2-pyrazolin-5-one class, has the chemical name 3-methyl-1-phenyl-2-pyrazolin-5-one. It is a white crystalline powder and is freely soluble in acetic acid, methanol, or ethanol, as well as slightly soluble in water or diethyl ether. Edaravone is available as a clear, colorless liquid provided as a sterile injection solution supplied for intravenous (IV) ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
ORD Simulation Prediction: Optical rotation refers to when a beam of polarized light passes through a substance,the plane of polarized light rotates at a certain angle relative to its own direction of motion. The property of rotating polarized light that a substance has is called optical rotation. Materials with optical rotation include crystals, spin-polarized molecules and chiral molecules. For ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Identification of Rate-limiting Reaction Steps: By analyzing the structure of the reaction intermediates and transition states, the rate-limiting steps of the reaction can be determined combined with kinetic methods. Several remarkable computational methods have been developed to search for the transition states and analyze the mechanism of the entire reaction. Scientists can therefore model the ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Computational pharmaceutics is able to provide rational, deductive, and knowledge-based strategies in pharmaceutics with the use of high performance computing systems. Scientists therefore apply this unique technology to build atomistic and coarse-grained models of pharmaceutical formulations, revealing more and more important mechanistic details. Alfa Chemistry provides a profound insight into ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
In chemical concepts, dominant skeleton refers to the core structure of small molecules. In computational chemistry and medicinal chemistry, the skeleton also has the same meaning. The discovery of active compounds with novel skelecton is a great challenge for modern medicinal chemistry. It can not only improve the efficacy and drug-like properties of molecules, but also help pharmaceutical ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Chlorquinaldol is monohydroxyquinoline, or quinolin-8-ol that is substituted by a methyl group at position 2 and chlorine at positions 5 and 7. It is a solid insoluble in water and the chemical name of chlorquinaldol is 5,7-dichloro-2-methyl-8-hydroxyquinoline. Chlorquinaldol is an antimicrobial agent used in the treatment of bacterial vaginosis. Alfa Chemistry offers high quality chlorquinaldol. ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Ancitabine Hydrochloride: Ancitabine hydrochloride is a white needle-like crystal or crystalline powder that is freely soluble in water, slightly soluble in methanol and ethanol, and almost insoluble in ether, benzene and chloroform. The chemical name of it is 2-methanolyl 2,3,3a,9a-tetrahydro-3hydroxy-6-imino-6H furan-(2',3',4,5)-oxazole(3,2a) pyrimidine hydrochloride. Ancitabine hydrochloride ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Cyclophosphamide: Cyclophosphamide, also known as cytophosphane, appears as a white to almost white crystalline powder with a slightly bitter taste. The chemical name of it is p-[N,N-bis-(2-chloroethyl)]-1-oxo-3-nitrogen-2-phosphocyclohexane-p-oxide monohydrate. Cyclophosphamide is a synthetic alkylating agent chemically related to nitrogen mustard with antineoplastic and immunosuppressive ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Cytarabine Hydrochloride: Cytarabine hydrochloride is a white to off-white crystalline with the chemical name 1-β-D-arabinofuranosyl-4-amino-2(1H)-pyrimidinone hydrochloride. Cytarabine hydrochloride is used in chemotherapy for white blood cell cancers, especially acute myeloid leukemia (AML). ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Pharmaceutical Glass: A large number of drugs are packaged in glass containers. Glass containers can be broadly classified into four types. They include, Type I glass containers (borosilicate glass/neutral glass), Type II glass containers (soda-lime-silica glass/ treated soda-lime glass/ de alkalized soda lime glass), Type III glass containers (regular soda lime glass) and Type IV glass ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Alfa Chemistry specializes in a wide range of testing and inspection services, as an internationally accredited inspection organization. Our diversified testing services are widely used in consumer products, including cosmetics, food and health products, pharmaceuticals, pharmaceutical packaging materials, disinfection products, clean rooms, herbal residues, pesticides, chemicals, ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Methotrexate, one of the earliest cancer chemotherapy agents, which is extensively used in the treatment of cancer, including breast cancer, leukemia, lung cancer, lymphoma, osteosarcoma and so on. The efficacy of methotrexate mainly due to its inhibitory effect on dihydrofolate reductase (DHFR)[1]. DHFR catalyzes the conversion of dihydrofolate to the active tetrahydrofolate that is needed for ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Sulfamethoxazole, a sulfanilamide, is a structural analog of para-aminobenzoic acid (PABA). It competes with PABA to bind to dihydropteroate synthetase and inhibits the conversion of PABA to dihydrofolic acid. Inhibition of this pathway ultimately prevents the synthesis of folate that is a critical role during DNA synthesis. Therefor, sulfamethoxazole can inhibit the growth and replication of ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Early studies on the properties of drugs in ADMET mainly focused on human-derived or humanized tissue functional proteins as drug targets. Combined with in vitro research techniques and computer simulation, scientists study the interaction between drugs and in vivo biophysical and biochemical barrier factors. Alfa Chemistry can predict ADME parameters and pharmacokinetic properties by calculating ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Ifosfamide has been effectively employed in the treatment of multiple cancers, including testicular cancer, soft tissue sarcoma, osteosarcoma, bladder cancer, small cell lung cancer, non-Hodgkin lymphoma, Hodgkin lymphoma, epithelial ovarian cancer, cervical carcinoma and germ cell carcinoma of the ovary[1]. Among all these cancers, the Food and Drug Administration (FDA) has approved ifosfamide ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Parecoxib sodium is a white or almost white crystalline powder with the chemical name sodium N-[4-(5-methyl-3-phenyl-1,2-oxazol-4-yl)benzenesulfonyl]propanecarboximidate which is freely soluble in water, methanol, N,N-dimethylformamide. Parecoxib sodium is an amide prodrug of the cyclooxygenase II (COX-2) selective, non-steroidal anti-inflammatory drug (NSAID) valdecoxib, with anti-inflammatory, ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Tofacitinib citrate, chemically named as (3R,4R)-3-[4-methyl-3-[N-methyl-N-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl]-3-oxopropionitrile citrate, is a white or almost white powder, which is lightly soluble in water, very slightly soluble in methanol, and practically insoluble in acetone. Tofacitinib citrate is a novel, oral Janus kinase (JAK) inhibitor for the treatment of rheumatoid ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
Lenalidomide can be used in the treatment of various of cancers and anemia in patients with certain blood/bone marrow disorders. Alfa Chemistry offers high quality of lenalidomide which meets the CP, EP & USP. Please feel free to contact us for APIs or technical services. Learn more at ...
Manufactured by:Alfa Chemistry based inNY, NEW YORK (USA)
SARS-CoV-2 Nucleocapsid Protein, His Tag: This product is specifically designed for serological test development. This product can be stored stably for 3 months under sterile conditions from −20 to −80 ...