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Drug Use Articles & Analysis
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Their impact is so great that safe and effective antiviral drugs have become an important tool in the fight against viral infections. ...
The applications of N-terminal Edman Degradation are vast and impactful. In drug development, it is used to verify the N-terminal sequences of therapeutic proteins, ensuring proper folding and functionality. ...
Challenges in Pharmaceutical Development Improving the dissolution, solubility, and bioavailability of poorly soluble drugs (BCS Class 2) remains a significant challenge. Amorphous Solid Dispersions (ASDs) are a promising solution, stabilizing drugs in their amorphous form using polymers and low-molecular-weight excipients. ...
Key chemical enhancers used include ethanol and azone, which interact with skin lipids to alter their arrangement, creating optimal pathways for drug molecules. ...
With Protheragen-ING’s microneedle technology, controlled drug delivery can be achieved using precise and efficient use of both hollow and solid structures made from any materials (silicons, metals or biodegradable polymers). The use of microneedles in transdermal drug delivery is much better than other ...
In medical applications, they’re used in cancer therapies and viral infection drugs. Alfa Chemistry makes this possible by providing pure and highly diverse nucleosides with modified versions used in the development of oligonucleotide therapeutics. ...
Before a new drug enters the market, its manufacturers would voluntarily submit drug master files (DMFs) to regulatory agencies like FDA. ...
Developing effective treatments for IPF has been a challenge for the medical community, as the mechanisms driving this disease are complex and not fully understood. To accelerate drug discovery, animal models that closely mimic the human disease are crucial. In this context, a recent study by Petersen et al (2024) has made significant strides in validating a well-known IPF mouse ...
A recent study by Yang, F., et al (2024) explores the potential of bacteriophage therapy for treating multi-drug resistant Mycobacterium tuberculosis (Mtb) infections using humanized mouse models. This study highlights the efficacy of phage DS6A in reducing Mtb load and improving lung function, with critical insights gained through advanced pulmonary function ...
CanaQuest Medical Corp (“CanaQuest” or the “Company”) (OTC: CANQF), is pleased to announce strategic additions to its executive team with expertise in conducting clinical trials and US FDA drug approval success. The team plans to effectively navigate the regulatory approval process for Drug Candidate, CQ-001 (cannabidiol + ...
Typically, the structures of such polymers are designed to reduce their dispersion in solution, thereby improving their stability and controllability. They’re widely used as drug carriers mainly because of their ability to efficiently carry and release drug molecules, thereby improving drug bioavailability and therapeutic ...
HLHS: HLHS is a rare pediatric disease affecting approximately 1000 live births per year in the US. The results of our successful Phase 1 trial showed 100% transplant free survival of all subjects at up to 5 years of age. ...
In recent years, the development of nanotechnology has had a tremendous impact on the development of novel nano-drug delivery systems. Various organic or inorganic materials have been used to prepare nano-drug delivery systems for safe and effective cancer therapy. PLGA-based drug delivery systems have attracted great interest ...
The newly introduced solutions are focused on long-acting controlled-release microspheres and phase-transition microneedle patches, to meet the growing demand for novel biopharmaceuticals and biosimilars, while at the same time, improving efficacy, safety, and convenience in drug delivery. Microsphere and microneedle technologies have been gaining increasing popularity in ...
Polymer Microspheres The polymer microspheres range in diameter from 1 to 200 microns and can be loaded with different drugs or bioactive molecules depending on the application. The microspheres can be injected or implanted into the target tissue or organ, allowing the drug to be released locally with minimal systemic effects. Polymeric microspheres are widely ...
BOC Sciences, a leading CRO in the USA, unveils its comprehensive capabilities for custom peptide drug conjugate from project design to commercial production. With its well-established conjugation platform, BOC Sciences supports pharmaceutical and biotechnology clients at the forefront of drug conjugation. Peptide-drug conjugates (PDCs) are ...
CO2 laser beauty machine is often used to treat patches, wrinkles, scars and warts on the face. Bvlaser is a professional CO2 laser beauty machine supplier. ...
“Our analysis and testing services will support pharmaceutical companies at every step and phase of the drug development lifecycle, making sure the entire drug development process complies with the latest regulatory standards and ...
Molecular docking is a key technique used in drug discovery and development, and it involves computationally predicting the binding of small molecules with the protein of interest. ...
Cardiovascular safety liabilities remain the major cause of costly drug withdrawals (e.g. 52.3 % drug withdrawals were cardiac safety related between 1980-2011). ...