Igg1 Articles & Analysis
9 news found
Gantenerumab is a fully-human monoclonal IgG1 antibody that was discovered in collaboration with Roche. “We are disappointed by these results as there are millions of people impacted every day by Alzheimer's disease,” said Jean-Paul Kress, M.D., Chief Executive Officer of MorphoSys. ...
Aflibercept solution for injection is a recombinant fusion protein, consisting of portions of extracellular domains of human VEGF receptors 1 and 2, fused to the Fc portion of human IgG1 and formulated as an iso-osmotic solution for intravitreal administration. ...
ByBayer AG
In addition, Amerigo Scientific offers a series of IHC guaranteed antibodies, including but not limited to Anti-Mouse IgG1 antibody (Catalog #: IGA1027831STJ), Anti-HLA-DR+DP antibody (Catalog #: IGA1027834STJ), and Anti-CD3 antibody(Catalog #: IGA1027835STJ). ...
ABOUT IO-202 IO-202 is a humanized IgG1 monoclonal antibody with high affinity and specificity towards LILRB4 (also known as ILT3). ...
In addition, AFM28 exhibits greater cell surface retention than conventional monoclonal antibodies, including Fc-enhanced IgG1. Furthermore, the data presented at the conference demonstrate that AFM28 stimulates lysis of CD123-positive tumor cells in both formats, pre-complexed or when co-administered with NK cells. ...
LAVA- 1207 is a bispecific antibody of 78 kDa, comprising two heavy chains, each consisting of a humanized VHH domain antibody and a human IgG1 modified hinge region, CH2 and CH3 domain. About LAVA Therapeutics LAVA Therapeutics N.V. is an immuno-oncology company utilizing its proprietary Gammabody™ platform to develop a portfolio of bispecific gamma delta T cell engagers ...
AV-380 Update AV-380 is a first-in-class, potent, humanized inhibitory IgG1 monoclonal antibody targeting growth differentiation factor 15 (GDF15), a potential treatment pathway for cancer and/or cachexia. ...
About Ficlatuzumab Ficlatuzumab (formerly known as AV-299) is a potent hepatocyte growth factor (HGF) immunoglobulin G1 (IgG1) inhibitory antibody that binds to the HGF ligand with high affinity and specificity. ...
Due to patients’ convenience of at-home administration and reduced number of hospital visits as well as the reduction in treatment costs, SubQ administration of biologics is of increasing interest. Trastuzumab targets Human IgG1/TNFα and is approved for breast cancer, gastric cancer, stomach and breast neoplasms across various geographies. ...