Metabolic Enzymes Articles & Analysis
8 news found
Creative Enzymes, a trailblazing leader in the field of enzyme research and manufacturing, is excited to announce its latest innovation: Diamine Oxidase (Food Grade). ...
It is therefore essential to predict metabolism for potential drug candidates. Current predictive models of metabolism usually target the human Cytochrome P450 (CYP) enzyme family, due to its well-characterised role in the metabolism of drug-like compounds. However, there is an increasing need to predict ...
After digestion, the amino acid sequence may undergo further amino acid modifications and be metabolized by hepatic P450 enzymes. In vivo metabolite studies of protein/peptide drugs usually focus on non-specific enzymatic cleavage or modification of amino acids, P450 enzyme metabolism, and multi-charge distribution. Metabolite ...
Creative Enzymes, a professional enzyme provider located in New York, USA, is always hammering at researches and trials in order to provide customers with various enzyme services and products as many as possible. With the technical escalation of its enzyme platform, the company is proud to launch fully-developed baking ...
Recently, the product manager of Creative Enzymes announced the technological upgrade of the Metabolic Flux Analysis service to quantify fluxes in both prokaryotic and eukaryotic systems. ...
HemoShear Therapeutics, Inc., a clinical stage company developing treatments for rare metabolic disorders, today announced the publication of in vitro pharmacology data in the journal Molecular Genetics and Metabolism, demonstrating that the oral small molecule HST5040 may be effective in treating Methylmalonic Acidemia (MMA) and Propionic Acidemia (PA). ...
The team also demonstrated that proteins called soluble epoxide hydrolase (sEH) inhibitors, known to elevate EET levels, promoted liver and lung regeneration. (sEH is the main metabolizing enzyme of EETs.) “Our results offer a mechanistic rationale for evaluating sEH inhibitors as novel therapeutics for a number of human diseases such as hepatic ...
'According to the study the glutathione S-transferases act to inactivate chemicals so people without these GSTM1 and GSTT1 genes are less able to metabolize environmental chemicals,” said Lourdes Salvador, Founder and President of MCS America. “If a person cannot metabolize chemicals they build up in the body and cause disturbances in normal body function,” added ...