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Target Protein Articles & Analysis
115 news found
This unique technology specifically targets lactoferrin, a major protein stored in neutrophil granules, making it possible to visualize and study these immune cells with unmatched precision. ...
These extracellular vesicles have a phospholipid bilayer structure and can carry important biological information, such as proteins, nucleic acids (e.g., microRNA and long non-coding RNA), and lipids. These extracellular vesicles, composed of cell membranes, can attach to target cells through surface adhesion proteins and carrier ligands, such as ...
Research on molecular targeted therapy for tumors is increasing, and new targeted therapeutic agents are emerging. ...
The topics set for the 2025 edition would highlight small-molecule drug discovery, novel modalities, and translational technologies with a particular focus on targeting protein degradation, RNA therapeutics, and precision drug delivery systems, which are all areas where BOC Sciences has built extensive expertise for years. BOC Sciences will ...
The N-terminal Edman Degradation technique, developed by Pehr Edman in the 1950s, remains a cornerstone of protein sequencing. It involves the sequential removal and identification of amino acids from the N-terminus of a polypeptide chain, providing unambiguous sequence data that is critical for understanding protein structure and function. ...
Always innovative and outstanding, Alfa Chemistry now has an extensive range of products within the pharmaceutical field, including PROTAC building blocks, nucleosides, intermediates and Active Pharmaceutical Ingredients (APIs). Proteolysis-targeting chimera (PROTAC) is a revolution in protein degradation. PROTACs take over the ubiquitin-proteasome system to ...
They are essential for the efficient transportation of mRNA to target cells, ensuring that therapeutic mRNA is delivered to the cytoplasm, where it can effectively produce the target protein. ...
These highly specific antibodies target the hexon protein of adenoviruses, making them a valuable tool for researchers studying these common pathogens. ...
The company's portfolio includes immune checkpoint proteins, CAR-T cell targets, CD antigens, fluorescent-labeled recombinant proteins, PROTAC targets, and more. ...
As CHO (Chinese Hamster Ovary) and HEK (Human Embryonic Kidney) cells are the most well-suited mammalian cell lines for recombinant protein production and biological research, this partnership represents a significant milestone in advancing biopharmaceutical development by providing ExcellGene’s pioneering transposon technologies to Cytovance’s biopharma customers. ...
CD BioSciences, a US-based CRO serving the global life science research community, has announced the launch of its new services to study the Mechanistic Target of Rapamycin (mTOR) in diabetes and metabolism research. The mechanistic Target of Rapamycin is a serine/threonine protein kinase that is inhibited by rapamycin, a bacterial compound ...
Amerigo Scientific, a distributor focused on providing critical products and services to biomedical and life science communities, is proud to showcase its featured offering in cell-free protein expression supplies - the pEU vector set. This innovative vector set allows for efficient and reliable protein expression in a cell-free system, offering researchers a ...
Protein-protein interactions serve as the building blocks of various cellular processes, orchestrating critical functions within living organisms. Gaining a deeper understanding of these intricate interactions is essential for deciphering disease mechanisms and identifying potential therapeutic targets. Far-Western Blot Analysis emerges as a ...
Taking this technology to new heights, CD Computabio's virtual screening service utilizes pharmacophore fragments, enabling unparalleled accuracy and speed in identifying potential drug targets. Pharmacophore fragments are essential chemical features that contribute to the biological activity of a molecule. By analyzing the three-dimensional arrangement of these fragments, CD ...
About FXIa inhibitors and Asundexian Factor XI is a protein in the blood which is converted into its active enzyme form (Factor XIa) as part of the blood coagulation cascade. FXIa inhibition specifically targets the FXIa protein involved in pathological thrombus formation, but leaves the pathway involved in the physiological healing of vessel ...
ByBayer AG
Peptides selected for PDCs can specifically target protein receptors overexpressed in tumor tissue and have strong binding affinity for the target site within nanomolar amounts, such as cell-targeting peptides (CTPs) and cell-penetrating peptides (CPPs). ...
Taking influenza viruses as an example, it detects antibodies targeting HA proteins of influenza viruses, thereby identifying functional strain-specific antibodies in human and animal sera. ...
His goal: to design antibodies that have a predetermined, desired effect on the function of a targeted protein. "Unlike the antibodies made by conventional antibody technologies, the promise of our approach is creating smart antibodies -- a sort of nanorobot that, like naturally occurring proteins, is able to adapt to changing situations," said ...
Denosumab is an antibody treatment that shows a strong bone resorption inhibitory effect by targeting the RANKL protein, which is essential for the survival and function of osteoclasts. ...
“Our programs are nearly all targeting proteins the industry has previously viewed as undruggable and indicate the potential to deliver enormous value to patients, if successful. ...
ByBayer AG