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Disease Modeling Equipment & Supplies In Norway
91 equipment items found
Manufactured by:Ncardia Services B.V. based inLeiden, NETHERLANDS
The discovery that transformed biological research. In 2007, Shinya Yamanaka and Kazutoshi Takahashi were able to reprogram human somatic cells into pluripotent stem cells by inducing the expression of four embryonic transcription factors. The resultant cells were called human induced pluripotent stem cells (iPSC). iPSCs have unlimited proliferation capacity and can be differentiated into nearly ...
Manufactured by:Systasy Bioscience GmbH based inMunich, GERMANY
The DiseasePROFILER uses a subset of top-performing sensors identified in the PathwayPROFILER assay and enables simple, robust, and cost-effective screening of compound effects in human disease models. ...
Manufactured by:vivoVerse Inc. based inAustin, TEXAS (USA)
Our large-scale microfluidic chip for high-throughput screening of C. elegans disease models at high-content, is published in Nature Communications (DOI 10.1038/ncomms13023). The platform enables high-resolution imaging and analysis of ~4,000 C. elegans from 96 different populations in approximately 15 minutes. ...
Manufactured by:Jiangsu Xietong Pharmaceutical Bio-engineering Co., Ltd. based inNanjing City, CHINA
Rodent Diet with 45% Calories from Fat (ref. D12451) and its adjusted formula are widely used in the establishment of obesity and type 2 diabetes and other disease models in rats, and its advantage lies in its stable modeling cycle and high modeling ...
Manufactured by:Jiangsu Xietong Pharmaceutical Bio-engineering Co., Ltd. based inNanjing City, CHINA
Rodent Diet with 60% Calories from Fat (ref. D12492) and its adjusted formula are widely used in the establishment of obesity and type 2 diabetes and other disease models in rats, and its advantage lies in its stable modeling cycle and high modeling ...
by:bit.bio based inCambridge, UNITED KINGDOM
Introducing highly-defined, consistent and reliable human muscle cells for research, disease modelling and high throughput screening across areas such as muscle, neuromuscular, and associated metabolic disorders. ioSkeletal Myocytes have been reprogrammed from human induced pluripotent stem cells (iPSCs) using our precise reprogramming technology: ...
Manufactured by:Auris Medical AG based inBasel, SWITZERLAND
The OligoPhore™ / SemaPhore™ technology has been extensively and successfully tested with various siRNA and mRNA sequences in numerous disease models in mice. For the development of our first proprietary drug product, AM-401 (OligoPhore™ siRNA targeting KRAS), we have initiated a program of IND-enabling ...
by:Reaction Biology Corp. based inMalvern, PENNSYLVANIA (USA)
The Biomarker Analysis tool identifies genes or genetic alterations which are indicative for the efficacy of a drug and which may serve as predictive biomarkers in disease models and patient ...
Manufactured by:InvivoSciences, Inc. (IVS) based inMadison, WISCONSIN (USA)
InvivoSciences (IVS) combines its human micro tissue technology and phenotypic assay platform with the systems biology approach to achieve rare disease modeling for its drug discovery. Our strip tissues are perfect for modeling muscle and connective tissue in micro-well plates. Since many rare diseases affect heart muscle and ...
Manufactured by:InSphero AG based inSchlieren, SWITZERLAND
The 3D InSight™ Steatosis Model is an advanced human disease model that enables you to screen compounds and investigate disease pathophysiology using a physiologically relevant human liver microtissue that recapitulates the first stage of non-alcoholic fatty liver disease: accumulation of lipids in ...
Manufactured by:Ncardia Services B.V. based inLeiden, NETHERLANDS
Astrocytes are essential players in neurodegenerative disease progression providing a valuable tool for drug discovery and disease modeling. Human iPSC-derived astrocytes generated with our standardized process express key identity markers and support co-culture with human iPSC-derived neurons. Our team can manufacture astrocytes at scale ...
Manufactured by:ROKIT Healthcare based inGeumcheon-gu, SOUTH KOREA
It is widely applicable to the fields of bioengineering and medicine, from in vitro applications in novel product screening, disease modeling, and animal alternative experimentation to in vivo applications in tissue transplantation and ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Tangeretin (Tangeritin), a flavonoid from citrus fruit peels, has been proven to play an important role in anti-inflammatory responses and neuroprotective effects in several disease models, and is a Notch-1 ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
MPTP hydrochloride is a brain penetrant dopamine neurotoxin. MPTP hydrochloride can be used to induces Parkinson’s Disease model. MPTP hydrochloride, a precusor of MPP+, induces apoptosis[1][2][3]. MPTP hydrochloride has been verified by MCE with professional biological ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
GSK-3 inhibitor 3 is a selective, orally active and brain-penetrant inhibitor of GSK-3, with IC50s of 0.35 nM and 0.25 nM for GSK-3α and GSK-3β, respectively. GSK-3 inhibitor 3 lowers levels of tau protein phosphorylation at S396 in a triple-transgenic mouse Alzheimer’s disease model, with IC50 of 10 nM. GSK-3 inhibitor 3 can be used for neurological ...
Manufactured by:AnaBios Corporation based inSan Diego, CALIFORNIA (USA)
Primary human cryopreserved hepatocytes are ideal for many scientific applications, including toxicity, metabolism, disease modeling, genomics, enzyme-mediated mechanisms, uptake, intrinsic clearance and more. When plated, human hepatocytes from the liver are metabolically active for 5-7 days and ideal for more extended studies, including transporter, induction ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
MPT0G211 can penetrate the blood-brain barrier. MPT0G211 ameliorates tau phosphorylation and cognitive deficits in an Alzheimer’s disease model. MPT0G211 has anti-metastatic and neuroprotective effects. Anticancer ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Sevasemten decreases muscle damage biomarkers and fibrosis while increasing muscle strength and activity in in Duchenne muscular dystrophy disease ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Melamine is an orally active inducer of Apoptosis. Melamine induces animal disease models. Melamine affects the activity of Sertoli cell and can be used for research on male reproductive function. Melamine also has neurotoxicity and nephrotoxicity. Melamine induces cognitive impairment and acute kidney injury models. Melamine can also be used to ...
Manufactured by:InSphero AG based inSchlieren, SWITZERLAND
Test efficacy of anti-NASH drugs in an advanced 3D human liver disease model. The InSphero 3D InSight™ Human Liver NASH Model consists of an advanced microtissue co-culture of healthy primary human liver cells combined with specially formulated media and cocktails that induce the progression of NAFLD and NASH from steatosis to liver ...