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Collagen Induced Equipment & Supplies
61 equipment items found
by:Abivax based inParis, FRANCE
In addition to the clinical observations in UC patients, Abivax generated excellent phase 2a clinical results in RA, following the promising pre-clinical data from collagen-induced arthritis animal ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
L-161982 is a selective EP4 receptor antagonist. L-161982 completely blocks PGE2-induced ERK phosphorylation and cell proliferation of HCA-7 cells. L-161982 alleviates collagen-induced arthritis in ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
SR-1903 is an inverse agonist of RORγ and PPARγ (IC50 of ∼100 nM and 209 nM for RORγ and PPARγ, respectively) and a LXR agonist. SR-1903 exhibits anti-inflammatory and anti-diabetic efficacy in collagen-induced arthritis and diet-induced obesity mouse ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
GLPG0259 is a ATP-competitive inhibitor of MAPK-activated protein kinase 5 (MK5) with oral activity. GLPG0259 reduces inflammation and bone destruction in a mouse model of collagen-induced arthritis. GLPG0259 also inhibited the metastasis of prostate cancer (PCa) ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
UNC2881 shows additional inhibition against Axl and Tyro with IC50s of 360 nM and 250 nM, respectively. UNC2881 potently inhibits collagen-induced platelet aggregation, can be used for pathologic thrombosis ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
TMI-1 (WAY-171318) inhibits TNF converting enzyme (TACE) (IC50 of 8.4 nM), ADAM-TS-4, ADAM-17 and various MMPs with oral activity. TMI-1 significantly suppresses the secretion of TNF-α , alleviating collagen-induced arthritis in mice. TMI-1 inhibits cancer cell proliferation, induces apoptosis through a caspase-dependent pathway. TMI-1 also ...
Manufactured by:MBP – Medical Biomaterial Products GmbH based inNeustadt-Glewe, GERMANY
MB-Collagen is a collagen based dressing for wound care and traumatic, slowly healing wounds like Decubitus or leg ulcers (Ulcus cruris). The effectiveness of MB-Collagen is based on one hand on the chemotactic effects of the collagen matrix leading to a settlement of fibroblasts on the wound bed. On the other hand exogen collagen promotes binding of proteases. Both mechanisms are acting ...
Manufactured by:MBP – Medical Biomaterial Products GmbH based inNeustadt-Glewe, GERMANY
Surgicoll Plug is a fully resorbable sponge like cone formed collagen matrix for effective hemostasis. Collagen is well known for its outstanding properties as hemostatic agent documented in numerous clinical reports. The sponge like collagen matrix promotes reliable blood clotting due to two complementarily acting mechanisms. While the ...
Manufactured by:MBP – Medical Biomaterial Products GmbH based inNeustadt-Glewe, GERMANY
Surgicoll is a fully resorbable sponge like collagen matrix for effective hemostasis. Collagen is well known for its outstanding properties as hemostatic agent documented in numerous clinical reports. The sponge like collagen matrix promotes reliable blood clotting due to two complementarily acting mechanisms. While the collagen ...
Manufactured by:Lohmann & Rauscher GmbH & Co. KG (L&R) based inRengsdorf, GERMANY
The Suprasorb C Collagen Wound Dressing has a porous structure with highly pronounced capillary activity, allowing absorption of fluid. This physical property allows continuous absorption of exudate, debris (such as necrotic tissue, fibrin slough) and inflammatory proteases and cytokines. This promotes and accelerates formation of granulation tissue. Migration of fibroblasts is ...
Manufactured by:MBP – Medical Biomaterial Products GmbH based inNeustadt-Glewe, GERMANY
Surgicoll Cloud is a fully resorbable microfibrillar collagen matrix for effective hemostasis. Collagen is well known for its outstanding properties as hemostatic agent documented in numerous clinical reports. The sponge like collagen matrix promotes reliable blood clotting due to two complementarily acting mechanisms. While the ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Icanbelimod (S1p receptor agonist 1) is a potent and orally active S1P receptor agonist, exhibits an activity of inducing S1P1 internalization (EC50=9.83 nM). Icanbelimod has the potential for the study of arthritis and EAE (experimental autoimmune encephalitis). Icanbelimod is extracted from patent WO2015039587A1, Compound ...
Manufactured by:Iskra Medical d.o.o. based inPodnart, SLOVENIA
A powerfull combination of ultrasound and RDT®technology leads to the unique vacuum cavitation treatment that entails highly effective and risk-free body contouring. The vacuum cavitation systems therefore provide non-invasive, painless,safe, and fast alternative to the liposuction procedures as well as effective cellulite reduction.Various body sites can be contoured with no anesthesia, no ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Abatacept (CTLA4lg) is a soluble fusion protein consisting of the extra-cellular domain of human CTLA4 and a fragment of the Fc portion of human IgG1 (hinge and CH2 and 3 domains)[1]. Abatacept is a selective T-cell co-stimulation modulator and a protein agent for the autoimmune ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Lupeol acetate is a derivative of Lupeol. Lupeol acetate is an anti-inflammatory, antibacterial, anti-trypanosomic and anticancer agent with oral activity. Lupeol acetate significantly improves the symptoms of rheumatoid arthritis by down-regulating the expression of inflammatory cytokines and osteoclast production. Lupeol acetate inhibits spermatogenesis in male rats and eventually led to ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Betahistine mesylate is an orally active histamine H1 receptor agonist and a H3 receptor antagonist[1]. Betahistine mesylate is used for the study of rheumatoid arthritis ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
JNJ-61803534 is a potent and orally active RORγt inverse agonist with an IC50 of 9.6 nM. JNJ-61803534 has anti-inflammatory activity. JNJ-61803534 inhibits IL-17A production in human CD4+ T cells under Th17 differentiation ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
CC-90001 is a potent, selective and orally active inhibitor of c-Jun N-terminal kinase (JNK). CC-90001 shows 12.9-fold selectivity for JNK1 over JNK2 in a cell-based model. CC-90001 can be used for the research of idiopathic pulmonary ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Y-320 is a potent, orally active phenylpyrazoleanilide immunomodulator. Y-320 inhibits IL-17 production by CD4 T cells stimulated with IL-15 with IC50 values of 20 to 60 nM. Y-320 enhances TP53, DMD, and COL17A1 PTC readthrough by G418 and increases cellular protein levels and protein synthesis. Y-320 concomitants use of with a low dose of Paclitaxel (HY-B0015) significantly sensitized multidrug ...
Manufactured by:MedChemExpress LLC (MCE) based inMonmouth Junction, NEW JERSEY (USA)
Betahistine is an orally active histamine H1 receptor agonist and a H3 receptor antagonist[1]. Betahistine is used for the study of rheumatoid arthritis ...