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Genome Equipment Supplied In Usa Massachusetts
30 equipment items found
Manufactured by:Editas Medicine based inCambridge, MASSACHUSETTS (USA)
Genomic medicine is a developing field of medical research that harnesses recent advances in genetics to develop new medicines for diseases. In fact, we are at an inflection point where we are seeing the first real genomic medicines emerge to help patients. Advances in the scientific fields of cell therapy and gene therapy have paved the way for the success of ...
by:Intellia Therapeutics, Inc. based inCambridge, MASSACHUSETTS (USA)
Genome editing is efficient, precise and scalable. CRISPR/Cas9 genome editing can make permanent, precisely targeted changes in patients’ chromosomes and repair the underlying genetic mutation, whereas more traditional gene therapy typically involves introducing a non-permanent copy of a gene into patients’ cells. These attributes of CRISPR/Cas9 ...
Manufactured by:LGC SeraCare based inMilford, MASSACHUSETTS (USA)
The AccuPlex™ SARS-CoV-2 Verification Panel – Full Genome contains three different concentrations of positive reference material for the entire SARS-CoV-2 genome. Also includes negative reference material directed against the human RNase P gene. The panel is optimized for assay verification at installation by documenting test performance along the ...
Manufactured by:LGC SeraCare based inMilford, MASSACHUSETTS (USA)
The AccuPlex SARS-CoV-2 Molecular Controls Kit – Full Genome contains positive reference materials for the entire SARS-CoV-2 genome. Also includes negative materials targeting the human RNase P gene. It is designed to measure day-to-day performance of the assay, providing both a positive and a negative reference ...
Manufactured by:AMS Biotechnology (Europe) Ltd. based inAbingdon, UNITED KINGDOM
SKU: HD-902-HR. Size: 30 reactions. Species: Human. Tissue Type: Bladder. Storage: -20C. Shipping TempGel: ...
Manufactured by:MaxCyte. based inWaltham, MASSACHUSETTS (USA)
ONE-seq has the advantages that it can be used to assess adenine and cytosine base editors, it allows variant-aware analysis of multiple genomes simultaneously (thousands), and it detects a broader spectrum of off-target sites. Target cells or tissues are then tested to confirm which of the nominated sites are altered after therapeutic gene ...
by:Day Zero Diagnostics Inc. based inBoston, MASSACHUSETTS (USA)
While sample preparation technologies enable the whole genome sequencing of pathogens directly from clinical samples, once the samples have been sequenced there is a critical need for robust algorithms to interpret the sequencing data. Our computational methods take the raw genomic data as input and transform them into the diagnostic results that can serve ...
by:Vor Biopharma based inCambridge, MASSACHUSETTS (USA)
Knocking out CD33 and CLL-1 through gene editing offers a promising new approach to treating patients with AML using our novel eHSC platform. Our research demonstrates that multiplex genome editing of allogeneic hematopoietic stem cells may represent another exciting strategy to efficiently and safely edit multiple genes in blood stem cells, allowing the potential use of ...
by:Intellia Therapeutics, Inc. based inCambridge, MASSACHUSETTS (USA)
The first patient was dosed with our investigational genome editing treatment for transthyretin (ATTR) amyloidosis in November 2020. Our modular approach enables us to optimize the power and versatility of the CRISPR/Cas9 technology and, importantly, allows us to rapidly develop therapeutics for numerous diseases that currently have limited treatment ...
by:Alexion Pharmaceuticals, Inc. based inBoston, MASSACHUSETTS (USA)
Developed in collaboration with leading children’s hospitals and technology and data-science companies, RARE ANSWERS tools are designed to deliver actionable data to physicians by analyzing phenotypic and genomic data and incorporating precision software, medical information, and clinical insights. Pilots of this approach have achieved world records in reducing the time to ...
by:Sumitomo Pharma Oncology, Inc. based inCambridge, MASSACHUSETTS (USA)
Menin is a scaffold nuclear protein that plays various key roles in biological pathways, including cell growth regulation, cell cycle control, genomic stability, bone development, and hematopoiesis.26,27 Binding of menin to MLL fusion and wildtype proteins leads to the upregulation of HOXA family and MEIS1 genes that function to stall myeloid cellular differentiation and induce ...
Manufactured by:LGC SeraCare based inMilford, MASSACHUSETTS (USA)
The Seraseq Tumor Mutation DNA Mix v2 (AF7) HC is a multiplexed mixture of actionable biosynthetic DNA targets precisely blended with a single, well-characterized genomic background. This product is produced under rigorous design control and manufacturing practices to an allelic frequency of 7%, and is offered in a high concentration (HC) format at 25 ng/µL. Designed to ...
Manufactured by:LGC SeraCare based inMilford, MASSACHUSETTS (USA)
Whole transcriptome RNA sequencing allows for the analysis of fusion genes with potential clinical utility that currently cannot be detected using the limited genomic coverage of targeted NGS panels. Additionally, some clinical cancer testing labs are evaluating whole transcriptome panels for improved diagnostic yields and clinical utilization for NGS-based tumor profiling test ...
Manufactured by:Kura Oncology, Inc. based inSan Diego, CALIFORNIA (USA)
This is a major advance over traditional chemotherapy, which can be as potent against healthy tissue as it is against cancer. Using tumor genomic profiling and biomarker strategies, physicians can select the patients most likely to respond well to targeted therapies. Yet, so far, due to exquisite selectivity of these new precision medicines, only relatively smaller patient ...
by:Kephera Diagnostics, LLC based inFramingham, MASSACHUSETTS (USA)
Kephera’s Zika project is based on the identification of Zika-specific and Dengue-specific epitopes within the viral genome, from which an immunoassay will be developed in convenient and cost-effective ELISA format, and ultimately translated to point-of-care format. To this end, we are working in collaboration with medical research institutes in the U.S. and Latin America ...
by:Myeloid Therapeutics based inCambridge, MASSACHUSETTS (USA)
Retrotransposons are genetic elements that can replicate through reverse transcription of an RNA transposition intermediate. They contribute to structural changes and, more importantly, to gene regulation. Our proprietary RNA-based, retrotransposon-mediated gene-insertion technology (CREATE) has applications across gene editing and ...
by:Ginkgo Bioworks Inc. based inBoston, MASSACHUSETTS (USA)
We use our circular RNA platform to vastly accelerate understanding of regulatory elements involved in transcription. What we deliver is a range of promoters/enhancers of varying strength and specificity designed for expression at the right time and place. Why optimize transcription? Transcriptional control is the primary method of cellular control and can work over a 100,000-fold range. Other ...
Manufactured by:Obsidian Therapeutics, Inc. based inCambridge, MASSACHUSETTS (USA)
Our proprietary cytoDRiVE® platform leverages drug responsive domains (DRDs) to control protein function using an FDA-approved small ...
by:Revvity Gene Delivery (formerly SIRION Biotech) based inHamburg, GERMANY
Adenoviral vectors offer high levels of transgene expression in broad cell types, including dividing and non-dividing cells. Adenoviral vectors are the method of choice whenever fast and transient gene expression for a very large gene or several genes is required, since the expression cassette has a total capacity of 7.5 kb. This provides space for flexible vector design with multiple transgenes ...
Manufactured by:Thermo Fisher Scientific based inWaltham, MASSACHUSETTS (USA)
Invitrogen TrueCut HiFi Cas9 Protein is a high fidelity CRISPR Cas9 protein variant engineered to demonstrate superior off-target profiles, while preserving maximum on-target editing efficiency. TrueCut HiFi Cas9 Protein is ideal for applications that are sensitive to off-target events and when more precise editing is ...