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T And B Cell Equipment Supplied In Europe
140 equipment items found
by:Evaxion Biotech A/S based inHørsholm, DENMARK
RAVEN combines the essential AI tools from our PIONEER platform with structural bioinformatic tools from EDEN to arrive at a novel potent T- and B-cell vaccine design for emerging and mutating viral ...
Manufactured by:Virasoft Inc. based inSarıyer, TURKEY
Programmed cell death protein 1 (PD-1; also called CD279) is one of the co-inhibitory receptors that is expressed on the surface of antigen-stimulated T cells [1]. Normally, PD-L1 expression can be detected on hematopoietic cells including T cells, B cells, ...
Manufactured by:Treos Bio Limited based inLondon, UNITED KINGDOM
At TREOS we discovered that an individual’s HLA genotype is the main determinant of immune responses. This breakthrough led to the development of the PEPI Test (CE Marked) that predicts peptide-specific T cell responses of HLA genotyped individuals. Based on the PEPI Test we have been co-developing with each PolyPEPI™ product a Companion Diagnostic to predict likely responders and ...
Manufactured by:Santa Cruz Biotechnology, Inc. based inDallas, TEXAS (USA)
Concanamycin A is a specific inhibitor of vacuolar type H+-ATPase activity (V-ATPase) and is capable of inducing ...
Manufactured by:TC BioPharm based inHolytown, UNITED KINGDOM
TCB007 is an unmodified allogeneic gamma delta T cell product, being used for the treatment of COVID-19. This product is at the CTA application stage and is expected to enter phase 1 trials in summer 2020. ...
Manufactured by:Genekam Biotechnology AG based inDuisburg, GERMANY
Genekam Human T-Cell Isolation kit: Magnetic separator, Isolation chemicals 5 ...
Manufactured by:Ardigen based inKraków, POLAND
Accelerate discovery and improve safety of TCR therapies using Artificial Intelligence. Following the unique opportunity for curing patients provided by the development of cell therapies (e.g. TCR discovery), Ardigen has set on the path to advance the field with its Artificial Intelligence platform. Many challenges stand in the way of successful therapy discovery and development. Let us know how ...
Manufactured by:Immudex ApS based inVirum, DENMARK
dCODE Dextramer technology enables the analysis of antigen-specific T cells by NGS or single-cell multi-omics. dCODE Dextramer adds a unique DNA barcode to the MHC Dextramer® reagent to detect antigen-specific T cells by NGS or single-cell multi-omics. High-avidity binding to T-cell receptors thanks to multiple MHC-peptide complexes. High-throughput screening with a unique barcode for each ...
Manufactured by:PeptaNova GmbH based inSandhausen, GERMANY
Phebestin is a synthetic inhibitor specifically targeting alanyl-aminopeptidase, also known as aminopeptidase N (APN). It plays a significant role in modulating the proliferation and function of human peripheral T cells. This compound, characterized by its (2S,3R)-3-amino-2-hydroxy-4-phenylbutanoyl-L-valyl-L-phenylalanine structure, is soluble in water, methanol, and DMSO, offering versatile ...
by:Genmab A/S based inCopenhagen V, DENMARK
DuoBody-CD40x4-1BB (GEN1042) is a proprietary bispecific antibody, jointly owned by Genmab and BioNTech, created using Genmab’s DuoBody® technology. It is being co-developed under an agreement in which the companies share all costs and future profits for the product on a 50:50 basis. CD40 and 4-1BB were selected as targets to enhance both dendritic cells (DC) and antigen-dependent ...
Manufactured by:Takeda Pharmaceutical Company Limited based inChuo-ku, JAPAN
Brentuximab vedotin (brand name: Adcetris) is a treatment for post-transplant consolidation, relapsed or refractory Hodgkin lymphoma (cancer of the lymphatic system distinguished by the presence of CD30-positive Reed-Sternberg cells), and systemic anaplastic large cell lymphoma (a type of aggressive T-cell ...
by:BlueSky Immunotherapies GmbH based inWien, AUSTRIA
The high level of interferon induced by the delNS vector activates immunological defence reactions against cancer. It also stimulates the production of antiviral ...
Manufactured by:Oxford Vacmedix UK Limited based inOxford, UNITED KINGDOM
In the image below the Recombinant Overlapping Peptide is the “Antigen” being presented to the T Cell Receptor (TCR). This then triggers the growth of T Cells that will recognise the same marker on cancer cells leading to their destruction. ...
by:Horizon Therapeutics plc based inSaint Kevin`s, IRELAND
A fusion protein binding CD40L on T cells, blocking their interaction with CD40-expressing B cells. We are investigating dazodalibep in focal segmental glomerulosclerosis as well as conducting Phase 2 trials in kidney transplant rejection, rheumatoid arthritis and Sjögren’s ...
by:Engine Gmbh based inHennigsdorf, GERMANY
The UniPEx protein expression library consists of 2 Arrays representing clones in 2 different modified vectors. In total, more than 100,000 sequenced clones from different protein expression libraries (human fetal brain, T-cells, lung) were analysed in depth for their coding potential. After in-frame analysis only clones with a confirmed in-frame ORF were selected and redundancy with respect to ...
Manufactured by:Immatics N.V. based inTuebingen, GERMANY
Immatics’ TCER molecules can be produced and purified utilizing established processes to manufacture ...
Manufactured by:ProImmune Ltd. based inOxford, UNITED KINGDOM
Human MR1 Tetramers detect MAIT cells with human MR1 tetramers. ProImmune is the leading commercial source worldwide for fluorescently labeled human MR1 tetramers. MR1 complexes bind to T cell receptors on mucosal-associated invariant T (MAIT) cells. MAIT cells have a particular specificity (as determined by the relevant MR1-binding small molecule ligand used), allowing identification, ...
by:Astraveus based inParis, FRANCE
In healthy patients T cells detect and kill sick cells. Cancer cells escape T cells recognition thanks to mutations. CAR-T cells (T cells equipped with a Chimeric Antigen Receptor) are artificially hardcoded to recognize and kill cancer cells. Multiple CAR-T therapies are commercially available but their access is limited by low manufacturing throughput and high prices. We use our exclusive ...
Manufactured by:MV BioTherapeutics SA based inBellinzona, SWITZERLAND
MV010/MV004, in cancer immunotherapy • Significant increase of tumor specific cytotoxic T cells infiltrating the tumor microenvironment by combining MV010/MV004 to anti-PD-L1 administration in murine models. • Significantly improved tumor eradication and resistance to subsequent grafting and improved survival in murine models. ...
Manufactured by:Adaptimmune LLC based inPhiladelphia, PENNSYLVANIA (USA)
Our ADP-A2M4 (MAGE-A4) SPEAR T-cell therapy is directed to a member of the MAGE family of cancer testis antigen expressed in a number of solid tumor cell types. The MAGE- A4 antigen is among the most commonly expressed cancer-testis antigens. We are conducting various trials with the ADP-A2M4 SPEAR T-cell in various solid ...