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Immune Checkpoint Equipment Supplied In China
4 equipment items found
Manufactured by:Elpiscience based inShanghai, CHINA
LAG3 is an immune checkpoint receptor known to suppress T cell activation. We designed ES005 to block LAG3 ligands, including MHC class II and FGL1. Through unique epitope binding, ES005 is able to recognize human LAG3 with high affinity. In preclinical studies, ES005 inhibited tumor growth both as a monotherapy and in combination with a PD-1 ...
Manufactured by:Elpiscience based inShanghai, CHINA
It has a unique mechanism of action as 4-1BB activation is dependent on PD-L1 binding. 4-1BB is a T cell co-stimulatory receptor and is a compelling immune checkpoint target. 4-1BB targeting antibodies being developed by multinational companies have exhibited dose-dependent liver toxicity in clinical trials, thereby limiting dose-escalation and ultimately their ...
by:Xiamen Spacegen Co., Ltd. based inxiamen, CHINA
Detection Gene:KRAS,BRAF,NRAS,PIK3CA,TP53,DYPD,ERBB2,UGT1A1 and MSI（8 genes +MSI）. Detection Significance:Guiding individualized diagnosis and treatment of colorectal ...
by:Xiamen Spacegen Co., Ltd. based inxiamen, CHINA
Using high-throughput sequencing to test the coding regions and exon-intron junctions of five genes (MLH1, PMS2, MSH2, MSH6, EPCAM) in the germline panel, and the same five genes plus the BRAF V600E mutation in the tissue-based panel. Detection Gene:MMR-related genes MLH1, MSH2, MSH6, PMS2 and EPCAM, BRAF gene V600E mutation. Detection Significance:Germline test as confirmed diagnosis of Lynch ...